Show the mechanism of reduction of nitrile to primary amine by using nikel boride, generated from NiCl2. 6H20 with NaBH4

Chemistry for Engineering Students
4th Edition
ISBN:9781337398909
Author:Lawrence S. Brown, Tom Holme
Publisher:Lawrence S. Brown, Tom Holme
Chapter3: Molecules, Moles, And Chemical Equations
Section: Chapter Questions
Problem 3.119PAE
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Show the mechanism of reduction of nitrile to
primary amine by using nikel boride,
generated from NiCl2. 6H20 with NaBH4
Transcribed Image Text:Show the mechanism of reduction of nitrile to primary amine by using nikel boride, generated from NiCl2. 6H20 with NaBH4
CO₂Me
CN
NMe
Boc
NiCl₂ 6H₂0
Na BH 4
MeOH, 0 to 60°C
CO₂ Me
NH ₂
NMe
Boc
Transcribed Image Text:CO₂Me CN NMe Boc NiCl₂ 6H₂0 Na BH 4 MeOH, 0 to 60°C CO₂ Me NH ₂ NMe Boc
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