Sickle cell anemia is a human genetic disorder caused by an autosomal recessive allele. A couple plan to marry  and want to know the probability that they will have an affected child. With your knowledge of Mendelian  inheritance, what can you tell them if (1) each has one affected parent and a parent with no family history of SCA  or (2) the man is affected by the disorder but the woman has no family history of SCA?

BIOLOGY:CONCEPTS+APPL.(LOOSELEAF)
10th Edition
ISBN:9781305967359
Author:STARR
Publisher:STARR
Chapter14: Human Inheritance
Section: Chapter Questions
Problem 4GP: An allele responsible for Marfan syndrome Section 13.4 is inherited in an autosomal dominant...
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Sickle cell anemia is a human genetic disorder caused by an autosomal recessive allele. A couple plan to marry 
and want to know the probability that they will have an affected child. With your knowledge of Mendelian 
inheritance
, what can you tell them if (1) each has one affected parent and a parent with no family history of SCA 
or (2) the man is affected by the disorder but the woman has no family history of SCA? 

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