Huntington’s disease, a neurodegenerative genetic disorder that typically becomes noticeable in middle age, is due to an autosomal dominant allele. Sickle cell anemia, on the other hand, is a genetic blood disorder due to a recessive allele. Jane is a carrier of the allele for sickle cell anemia but has no sign of any neurodegenerative disorder in her family. She married Paul whose father died of Huntington’s disease. His mother, however, is not inflicted with that condition. Neither of his parents exhibit sickle cell anemia. What are the genotypes of Jane and Paul? If they plan to have four children, what is the probability that: all their children will be normal? _________________________________ they will have a son with Huntington’s disease? _________________________ they will have a daughter inflicted with both conditions?________________
Huntington’s disease, a neurodegenerative genetic disorder that typically becomes noticeable in middle age, is due to an autosomal dominant allele. Sickle cell anemia, on the other hand, is a genetic blood disorder due to a recessive allele. Jane is a carrier of the allele for sickle cell anemia but has no sign of any neurodegenerative disorder in her family. She married Paul whose father died of Huntington’s disease. His mother, however, is not inflicted with that condition. Neither of his parents exhibit sickle cell anemia. What are the genotypes of Jane and Paul? If they plan to have four children, what is the probability that: all their children will be normal? _________________________________ they will have a son with Huntington’s disease? _________________________ they will have a daughter inflicted with both conditions?________________
Human Biology (MindTap Course List)
11th Edition
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cecie Starr, Beverly McMillan
Chapter20: Chromosomes And Human Genetics
Section: Chapter Questions
Problem 7CT: The following pedigree shows the pattern of inheritance of red-green color blindness in a family....
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Huntington’s disease, a neurodegenerative genetic disorder that typically becomes noticeable in middle age, is due to an autosomal dominant allele. Sickle cell anemia, on the other hand, is a genetic blood disorder due to a recessive allele. Jane is a carrier of the allele for sickle cell anemia but has no sign of any neurodegenerative disorder in her family. She married Paul whose father died of Huntington’s disease. His mother, however, is not inflicted with that condition. Neither of his parents exhibit sickle cell anemia.
What are the genotypes of Jane and Paul?
If they plan to have four children, what is the probability that:
- all their children will be normal? _________________________________
- they will have a son with Huntington’s disease? _________________________
- they will have a daughter inflicted with both conditions?________________
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