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- Nifedipine is an antihypertension medication that is also used to reduce the workload on the heart. The study below compares the effects of two different types of capsules used to administer the drug to patients (GITSred line, and Cotracten Xblue line). Each graph shows changes with time following initial administra- tion of the capsules. Figure A compares the levels of nifedipine in the blood with each capsule type. The ability of the different cap- sules to reduce workload on the heart by altering blood pressure or heart rate is shown in Figures B and C, respectively. Are elevated plasma levels of nifedipine(above 10 ng/mL) required for the drug to perform its actions? Source: M. J. Brown and C. B. Toal. 2008. Formulation of long-acting nifedipine tablets influences the heart rate and sympathetic nervous system response in hypertensive patients. British Journal of Clinical Pharmacology 65:646652.Nifedipine is an antihypertension medication that is also used to reduce the workload on the heart. The study below compares the effects of two different types of capsules used to administer the drug to patients (GITSred line, and Cotracten Xblue line). Each graph shows changes with time following initial administra- tion of the capsules. Figure A compares the levels of nifedipine in the blood with each capsule type. The ability of the different cap- sules to reduce workload on the heart by altering blood pressure or heart rate is shown in Figures B and C, respectively. Which type of capsule would you expect to have fewer side effects? Source: M. J. Brown and C. B. Toal. 2008. Formulation of long-acting nifedipine tablets influences the heart rate and sympathetic nervous system response in hypertensive patients. British Journal of Clinical Pharmacology 65:646652.The measurement of what analyte is clinically useful in distinguishing cardiac from noncardiac causes of dyspnea? 1) TnT 2) CKMB 3) NT-proBNP 4) Homocysteine no references, just homework
- Which of the following is not an extensive property The combination of equivalent amounts of acids and bases is called? What is the correct sequence of the different stages in blood clotting? I Fibrinogin thrombin fibrin/II Prothrombin thromboplastin Thrombin CaPlasma proteins that are late acute phase reactants include all the following except? a. haptoglobin b. ceruloplasmin c. complement C3, C4 d. transthyretinWhich of the following routes is used to obtain a steady-state concentration in plasma? a. Single intravenous bolus dose b. Single oral dose c. Intravenous infusion d. Single subcutaneous route
- What will be the value of e –ketat a steady state when drug is given as Intravenous infusion?One of the more common adverse effects of cancerchemotherapy is the destruction of leukocytes. Before hisnext scheduled chemotherapy treatment, a patientundergoes a blood test called an absolute neutrophil count(ANC), which reveals that his neutrophil count is 1900 cells per microliter. Would his healthcare team be likely toproceed with his chemotherapy treatment? Why?A patient has frequent episodes of paroxysmal atrial fibrillation. He has received a medication for prophylaxis of these events. Which of the following is the most suitable for long term use? Nifedipine Adenosine Amiodarone Heparin Lidocaine
- Patients with a history of heart failure often get this history from chronic hypertension. Chronic hypertension leads to a condition called hypertrophic heart disease, or hypertrophic cardiomyopathy. This means that the heart muscle gets bigger, allowing less room for it to fill with blood. If these patients take beta blockers, such as metoprolol, it will benefit them because the heart will not overwork and grow in size. However, if a patient has pulmonary edema, how could the beta blocker make this patient worse?How do I calculate effective dose with a given equivalent dose, to the different organs.Please give an example with a formula of this : E = ∑ WTHWhere WT is the tissue weighting factorand H is the Equivalent dose.including step by step is highly appreciated.! ThanksAbout radiation thingWhile downhill skiing, Jerry lost control and appeared to hit into a tree, chest first. The ski patrol that are also certified in EMT reported that Jerry was found with his head cocked at a peculiar angle and it looked like he had a fracture at the position of the C2 vertebra. During triage, Jerry appeared cyanotic and apneic. His heart was still beating, but his pulse was fast and thready. b) What would be the best possible explanation for the cyanosis?