The carbonyl carbon is electrophilic and can undergo nucleophilic attack by carbon, oxygen, sulfur and nitrogen-containing nucleophiles. In this tutorial, we will focus on oxygen-containing nucleophiles, which form hydrates, hemiacetals and acetals. This tutorial will cover 1. formation of geminal diols or hydrates and when this reaction is favorable 2. formation of hemiacetals 3. formation of acetals 4. hydrolysis of hemiacetals and acetals 5. acetals as protecting groups Ⓒ Macmillan Learning Step 4: The acetal formation mechanism is also reversible. The reaction can be driven in the forward reaction by using an excess of alcohol and driven in the reverse direction by using an excess of water. Analyze the reaction shown: excess H₂O* ? Select the product(s) of the reaction. OH HOCH₂CH₂OH Å -OH
The carbonyl carbon is electrophilic and can undergo nucleophilic attack by carbon, oxygen, sulfur and nitrogen-containing nucleophiles. In this tutorial, we will focus on oxygen-containing nucleophiles, which form hydrates, hemiacetals and acetals. This tutorial will cover 1. formation of geminal diols or hydrates and when this reaction is favorable 2. formation of hemiacetals 3. formation of acetals 4. hydrolysis of hemiacetals and acetals 5. acetals as protecting groups Ⓒ Macmillan Learning Step 4: The acetal formation mechanism is also reversible. The reaction can be driven in the forward reaction by using an excess of alcohol and driven in the reverse direction by using an excess of water. Analyze the reaction shown: excess H₂O* ? Select the product(s) of the reaction. OH HOCH₂CH₂OH Å -OH
Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter16: Aldehydes And Ketones
Section: Chapter Questions
Problem 16.45P: The following bicyclic ketone has two -carbons and three -hydrogens. When this molecule is treated...
Related questions
Question
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
Step by step
Solved in 3 steps with 3 images
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Recommended textbooks for you
Organic Chemistry
Chemistry
ISBN:
9781305580350
Author:
William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:
Cengage Learning
Organic Chemistry: A Guided Inquiry
Chemistry
ISBN:
9780618974122
Author:
Andrei Straumanis
Publisher:
Cengage Learning
Organic Chemistry
Chemistry
ISBN:
9781305580350
Author:
William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:
Cengage Learning
Organic Chemistry: A Guided Inquiry
Chemistry
ISBN:
9780618974122
Author:
Andrei Straumanis
Publisher:
Cengage Learning