The Drosophila gene Dscam1 encodes proteins on thesurface of nerve cells (neurons) that govern neuronalconnections. Each neuron has on its surface a singleDscam1 protein of the tens of thousands that exist.The particular Dscam1 protein a neuron expresses isthought to tag the cell uniquely to determine the pathsof the axons and dendrites it will grow. Eukaryoticgenes are monocistronic. How then can a singleDscam1 gene encode tens of thousands of differentproteins?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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The Drosophila gene Dscam1 encodes proteins on the
surface of nerve cells (neurons) that govern neuronal
connections. Each neuron has on its surface a single
Dscam1 protein of the tens of thousands that exist.
The particular Dscam1 protein a neuron expresses is
thought to tag the cell uniquely to determine the paths
of the axons and dendrites it will grow. Eukaryotic
genes are monocistronic. How then can a single
Dscam1 gene encode tens of thousands of different
proteins?

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