The enzyme lysozyme catalyses the hydrolysis of the polymer that consists of N-acetylglucosamine (NAG) and N-acetylmuramicacid (NAM). This reaction usually takes place at pH = 5, but is dramatically inactivated above a pH of 7. Explain why this occurs by referring to the catalytic mechanism of lysozyme.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter18: Glycolysis
Section: Chapter Questions
Problem 25P: Using the ActiveModel for phosphofructokinase (Trypanosoma), describe the difference between the...
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The enzyme lysozyme catalyses the hydrolysis of the polymer that consists of N-acetylglucosamine (NAG) and N-acetylmuramicacid (NAM). This reaction usually takes place at pH = 5, but is dramatically inactivated above a pH of 7. Explain why this occurs by referring to the catalytic mechanism of lysozyme.

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