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The following data were obtained following the administration of a single 100 mg oral dose of an experimental drug. calculate the equation which describes the plasma profile of the drug: Calculate the E and A values; and the k and ka values Time(hr)  Concentration (mg/L) 0.5                         5.41 1                              8.73 1.5                           10.212 2                             10.948 2.5                          11.034 3                              10.705 4                              9.405 6                                6.313 9                                3.029 10                             2.336 12                              1.45 14                             0.75

The following data were obtained following the administration of a single 100 mg oral dose of an experimental drug. calculate the equation which describes the plasma profile of the drug: Calculate the E and A values; and the k and ka values Time(hr)  Concentration (mg/L) 0.5                         5.41 1                              8.73 1.5                           10.212 2                             10.948 2.5                          11.034 3                              10.705 4                              9.405 6                                6.313 9                                3.029 10                             2.336 12                              1.45 14                             0.75

General, Organic, and Biological Chemistry
General, Organic, and Biological Chemistry
7th Edition
ISBN:9781285853918
Author:H. Stephen Stoker
Publisher:H. Stephen Stoker
Chapter8: Solutions
Section: Chapter Questions
Problem 8.16EP
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The following data were obtained following the administration of a single 100 mg oral dose of an experimental drug. calculate the equation which describes the plasma profile of the drug: Calculate the E and A values; and the k and ka values
Time(hr)  Concentration (mg/L)
0.5                         5.41
1                              8.73
1.5                           10.212
2                             10.948
2.5                          11.034
3                              10.705
4                              9.405
6                                6.313
9                                3.029
10                             2.336
12                              1.45
14                             0.75
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