The following figure below is the structure of Probenecid. What is the effect of the addition of this drug together with Penicillins? HO,C- N(CH,CH,CH3)2 a. It'slows down the rate of excretion of penicillins by blocking the facilitated transport mechanism in the kidney tubules b. It prevents the hydrolysis of the B-lactam ring by acting as a suicide inhibitor c. It improves the absorption in the gastrointestinal tract of penicillins by masking polar groups d. It inhibits the renal dihydropeptidase I which protects it from further metabolism
The following figure below is the structure of Probenecid. What is the effect of the addition of this drug together with Penicillins? HO,C- N(CH,CH,CH3)2 a. It'slows down the rate of excretion of penicillins by blocking the facilitated transport mechanism in the kidney tubules b. It prevents the hydrolysis of the B-lactam ring by acting as a suicide inhibitor c. It improves the absorption in the gastrointestinal tract of penicillins by masking polar groups d. It inhibits the renal dihydropeptidase I which protects it from further metabolism
Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter30: Nutrition
Section: Chapter Questions
Problem 30.35P
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