The following reaction is possible using a 4-step synthesis (putting 4 reaction schemes together in a specific order to give the desired product). Choose the correct 4-step reaction sequence to create the product below from the starting material and reagents shown. Your answer should be formatted using the number of the first reagent, followed by the number of the second reagent, followed by the third reagent, until you have selected the correct reagents and placed them in the correct order for the synthesis below. As with many syntheses, there may be more than one way to make the desired product from the starting material and reagents shown, but only provide one reasonable 3-step synthesis in the box provided below. An example of the correct answer format would be 2318 if you thought reagent #2 should come first, followed by reagent #3, and then lastly, reagents #1 and #8. Again, this synthesis only has 4 steps, so pick the correct reagents and place them in the correct order. Note: your answer may have 5 or more numbers since some of the reagents have double digits...not to worry, just put them in the right order with no spaces. It might be a good idea to try to work it out first on your scratch paper. Do not add any spaces in your answer.
The following reaction is possible using a 4-step synthesis (putting 4 reaction schemes together in a specific order to give the desired product). Choose the correct 4-step reaction sequence to create the product below from the starting material and reagents shown. Your answer should be formatted using the number of the first reagent, followed by the number of the second reagent, followed by the third reagent, until you have selected the correct reagents and placed them in the correct order for the synthesis below. As with many syntheses, there may be more than one way to make the desired product from the starting material and reagents shown, but only provide one reasonable 3-step synthesis in the box provided below. An example of the correct answer format would be 2318 if you thought reagent #2 should come first, followed by reagent #3, and then lastly, reagents #1 and #8. Again, this synthesis only has 4 steps, so pick the correct reagents and place them in the correct order. Note: your answer may have 5 or more numbers since some of the reagents have double digits...not to worry, just put them in the right order with no spaces. It might be a good idea to try to work it out first on your scratch paper. Do not add any spaces in your answer.
Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter14: Elimination
Section: Chapter Questions
Problem 24CTQ
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Concept explainers
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
Question
Transcribed Image Text:The following reaction is possible using a 4-step synthesis (putting 4 reaction schemes together in a specific order to give the
desired product). Choose the correct 4-step reaction sequence to create the product below from the starting material and
reagents shown. Your answer should be formatted using the number of the first reagent, followed by the number of the second
reagent, followed by the third reagent, until you have selected the correct reagents and placed them in the correct order for the
synthesis below. As with many syntheses, there may be more than one way to make the desired product from the starting
material and reagents shown, but only provide one reasonable 3-step synthesis in the box provided below.
An example of the correct answer format would be 2318 if you thought reagent #2 should come first, followed by reagent #3,
and then lastly, reagents #1 and #8. Again, this synthesis only has 4 steps, so pick the correct reagents and place them in the
correct order. Note: your answer may have 5 or more numbers since some of the reagents have double digits...not to worry,
just put them in the right order with no spaces. It might be a good idea to try to work it out first on your scratch paper. Do not
add any spaces in your answer.
4 steps
1. Hg(OAc)2, H₂O
1. BH3, THF
H₂
2. NaBH4
2. H₂O2, H₂O, OH
Lindlar's cat.
Reagent 1
Reagent 2
Reagent 4
H₂O+
H₂C-
HBr
H₂O₂
Reagent 5
Reagent 6
Reagent 8
EtOH
HBr
heat
Reagent 9
Reagent 10
Reagent 12
H₂
Pd/C
Reagent 3
CH₂1₂
Zn(Cu)
Reagent 7
NaNH,
Reagent 11
|||
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