The light-chain genes remain in the germline configuration. (Select all that apply.) Stem cell Early pro-B cell Late pro-B cell Large pre-B cell Small pre-B cell Immature B cell Mature naive B cell
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- At what stage of B cell development are autoreactive cells removed? A. stem cell stage B. pro-B cell stage C. early pre-B cell stage D. late pre-B cell stage E. immature cell stageIn which cells are the enzyme TdT actively functioning? (select all that apply) Select one or more: a. immature B cells b. plasma cells c. hematopoietic stem cells d. pro-B cellsFigure 17.17 The Rh antigen is found on Rh-positive red blood cells. An Rh-negative female can usually carry an Rh-positive fetus to term without difficulty. However, if she has a second Rh-positive fetus, her body may launch an immune attack that causes hemolytic disease of the newborn. Why do you think hemolytic disease is only a problem during the second or subsequent pregnancies?
- Match the immune cell with its main function. ___dendritic cell a. professional phagocyte ___B cell b. antigen-presenter ___helper T cell c. activates other lymphocytes ___NK cell d. makes antibodies ___macrophage e. kills ailing body cells that lack MHC markersMatch the stage of B-cell development in Column A with the rearrangement or expression status of the immunoglobulin genes in Column B._______ involves successive rearrangement at the lightchain loci when reactivity to self antigen occurs during B-cell development. a. receptor editing b. somatic hypermutation c. chromosomal translocation d. clonal deletion e. anergy.
- of the choices, which cells stimulate directly B cells to divide and produce antibodies? a. mast cells b. marcophages c. Nk cells d. TH cellsThe primary B-cell receptor isa. IgD b. IgA c. IgE d. IgGWhich statement is incorrect?a. IgG is the most abundant antibody in bloodb. Antibodies can exist at the surface of a B cell, or circulate freely in blood.c. IgM is found in the lining of the genitourinary, gastrointestinal and respiratory tractsd. IgE is involved allergic reactionse. Macrophages are involved in chronic infections