The product below can be synthesized by a Robinson annulation, which is a Michael addition followed by an aldol condensation/elimination. Draw the starting materials you would use. Also draw the structure of the intermediate after the Michael addition is completed, but before the aldol reaction has started.

Q: The Robinson annulation reaction yields a six membered ring resulting from a Michael reaction with…

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Q: A different way of synthesising the product 4,4- diphenylbut-3-en-2-one is via an aldol…

A: aldol condensation is a condensation reaction  in which an  enolate ion reacts with a carbonyl…

Q: Draw the major product of this aldol addition reaction. Ignore inorganic byproducts. 1. LDA 2.…

A: We have to draw the product of the given aldol reaction.

Q: Which of the following ketones would be the best choice to use for a crossed aldol reaction with…

A: In this question, we will see that which ketones worked equally well for crossed Aldol Condensation…

Q: Use the curved arrow formalism to draw the complete mechanism for the aldol addition reaction. (It…

A: Initially one Molecule of butyraldehyde reacts with potassium Hydroxide base, where OH- ions acts as…

Q: The first step of the dimedone reaction involves an aldol reaction. Here is a simpler version -…

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Q: Complete the following base-catalyzed Self-Aldol Condensation reaction mechanism. Draw the structure…

A: Reactant is cyclohexanone. It has alpha hydrogens which in the presence of a base can be extracted…

Q: Draw the product of each attached directed aldol reaction.

A: LDA is the hindered base. It abstracts the proton from the least hindered α-C to form enolate ion…

Q: Draw the product of the reaction of the following compound with a base:

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Q: Draw the starting material that would be needed to make this product through an intramolecular…

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Q: Explain the below attached question

A: a) In cross aldol condensation reactions, one of the carbonyl compound is a keto or aldehyde group…

Q: Dehydration via an E1cb mechanism Michael Reaction Intramolecular Aldol Reaction А C KOH / ETOH /…

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Q: Draw the structure of the major aldol product (prior to possible dehydration) of the following…

A: The given reaction is Aldo condensation reaction , here the ketone will form the enolate ion because…

Q: Draw the structure of the major aldol product (prior to possible dehydration) of the following…

A: The reaction taking place is given as,

Q: Draw the product of the reaction of the following compound with a base:

A: Given diketone compound,

Q: b. Show what combination of aldehyde, ketone, and/or ester can prepare each compound below. Every…

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Q: OH

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Q: 1) Which one of the following compounds cannot react with another equivalent of itself in an aldol…

A: As per our guidelines we are supposed to solve only the first question. Please post other questions…

Q: Draw the reaction mechanism and predict the product of the aldol condensation between benzaldehyde…

A: Here we are required to draw the mechanism for aldol condensation reaction

Q: Draw the two carbonyl compounds which could be used to make the enone shown below via the aldol…

A: Applying concept of Aldol reaction.

Q: Show the detailed reaction mechanism symmetrical aldol condensation of propanal to…

A: Solution: Symmetrical Aldol condensation is nothing but the Aldol condensation of same substrate ( a…

Q: 2. Illustrate detailed mechanisms for below attempted aldol reaction. CH3 CH' H. H. NAOH CH3

A: Aldol reaction involves the formation of an enolate ion in the presence of a strong base for which a…

Q: NaoH

A: Two carbonyl compounds, out of which one has an α-H atom, when react with each other form β-hydroxy…

Q: Draw the major product of the aldol addition reaction. Ignore inorganic byproducts. H 1. NaOH 2.…

A: In Aldol reaction first of all base abstract acidic hydrogen and form enolate ion. Then enolate ion…

Q: Draw the structure of the major aldol product (prior to possible dehydration) of the following…

A: An aldol condensation is a condensation reaction in organic chemistry in which an enol or an enolate…

Q: Draw the structure of the 1,3-diketone and conjugated ketone which may be used to make the Robinson…

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Q: Draw the structure of the major organic product of the following reaction. Predict whether the…

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Q: H СНЗ А cyclopentyl methyl ketone В Show the mechanism of a crossed aldol reaction starting with…

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Q: Draw the major product of the aldol addition reaction between two of these aldehydes with the…

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Q: Draw the major product obtained when each of the following compounds is heated in the presence of a…

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Q: NaOH +

A: Acetophenone and benzaldehyde in presence of base NaOH undergoes Claisen-Schmidt condensation…

Q: Show how to prepare each a,B-unsaturated aldehyde condensation. or ketone by an aldol

A: With alpha hydrogen containing carbonyl compounds in presence of dilute base follwed by heating…

Q: Choose all the compounds that will be able to produce aldol condensation product from the reaction…

A: Aldol condensation: It is type of condensation reaction in which enolate or enol reacts with…

Q: В. "GREEN CHEMISTRY": SOLVENT FREE ALDOL-CONDENSATION REACTION. i) Reaction H3CO NaOH H3CO H3CO OCH3

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Q: 3. Show how the following compound can be synthesized using an Aldol Condensation reaction.

A: Aldol condensation is a condensation reaction in which aldehyde having alpha-hydrogen reacts with…

Q: NaOH + CH3 H3C `CH2CH3 `CH3 Ob. H3C CHCH3 H2C `CH2CH3 d. CH2

A: In a chemical reaction; the substance involves in conversion is said to be reactant whereas the…

Q: Provide complete mechanisms and the products for each step of the following Robinson annulation (3…

A: We have to carry out the given reaction. This is an example of Robinson's annulation reaction.

Q: NaOH H. H,O

A: The question is based on the concept of organic mechanism. we have to explain the mechanism of aldol…

Q: Why is the enone product favored to be formed under the shown conditions rather than the aldol…

A: E1cB (Elimination Unimolecular Conjugate base) reaction involves the elimination of poor leaving…

Q: The Henry reaction is similar to what reaction you learned previously? Aldol condensation Robinson…

A: Note: Since you have asked multiple questions, we will solve the first for you. If you want any…

Q: b. ) What starting compound would you use in an Aldol condensation in the following compound?…

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Q: 13. Please draw the major product for each of the following three reactions

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Q: 2 teo NaOH, H₂O, A NaOH, H₂O, A 1. Me₂CuLi 2. H₂O Hint: Intramolecular aldol Hint: Aldol between two…

A: Note- Since the given question is a multipart question, hence I solved first three questions…

Q: For each compound shown below, draw the carbonyl compound and the nucleophile that were reacted to…

A: Given compounds are made-up from carbonyl compounds.

Q: If a student is starting with diethylmalonate then the base they would use to generate the enolate…

A: These are example of nucleophilic addition reaction

Q: NaOH dibenzalacetone beraldehyde acetone

A: Given reaction,

Q: What is the reaction mechanism for this final step in an Aldol Condensation

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Q: A Robinson annulation reaction, which always generates a 2-cyclohexenone as the fused ring, is a…

A: Robinson annulation reaction is used for synthesis of a six membered ring In this Robinson…

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.