Chapter21: Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions
Section21.SE: Something Extra
Problem 30VC
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- The reaction of an ester with an
amine is not as slow as the reaction of an ester with water or an alcohol. Explain with reason. - Explain why the rate of aminolysis of an ester cannot be increased by H+, OH- or OR-.
- How can you activate the carboxylic acid?
- Is acid catalyzed hydrolysis of acetamide a reversible or an irreversible reaction. Explain.
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