The Structure of the acetylcholine receptor is shown below: D. Briefly indicate what the role of the acetylcholine receptor is in an action potential.
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The Structure of the acetylcholine receptor is shown below:
D. Briefly indicate what the role of the acetylcholine receptor is in an action potential.
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- Assume presynaptic excitatory neuron A terminates on a postsynaptic cell near the axon hillock and presynaptic excitatory neuron B terminates on the same postsynaptic cell on a dendrite located on the side of the cell body opposite the axon hillock. Explain why rapid firing of presynaptic neuron A could bring the postsynaptic neuron to threshold through temporal summation, thus initiating an action potential, whereas firing of presynaptic neuron B at the same frequency and the same magnitude of EPSPs may not bring the postsynaptic neuron to threshold.A common membrane-bound intermediary between the receptor and the effector protein within the plasma membrane is the __________________.Conformational changes in channel proteins brought about by voltage changes are responsible for opening and closing Na+ and K+ gates during the generation of an action potential. (True or false?)
- If the postsynaptic cell's plasma membrane were to become substantially more permeable to Na+, you would expect the membrane potential to [depolarize, hyperpolarize] __________________. You would expect the membrane potential to depolarize if the extracellular K+ concentration were to [increase, decrease] ______________. a.) hyperpolarize, decrease b.) depolarize, decrease c.) depolarize, decrease d.) hyperpolarize, increaseWhat properties of ion channels allow them to generate the large, rapid changes in membrane potential?What is the expected resting membrane potential (in mV) of a neuron that is typical in all ways except for possessing an intracellular potassium concentration of 94 mM and double the normal resting permeability to sodium?
- If extracellular [Na1] is elevated, how would the resting potential and action potential of a neuron change?The resting membrane potential of a neuron typically is 70 mV. What does this mean?If a postsynaptic cell has synapses from five different cells, and three cause EPSPs and two of them cause IPSPs, give an example of a series of depolarizations and hyperpolarizations that would result in the neuron reaching threshold.
- Describe the ion concentration gradients across the plasmamembrane of a neuron at resting potential.Why is the resting membrane potential a negative value? And how do you determine resting membrane potential?Describe the contribution of each of the following to the establishment and maintenance of membrane potential: Part A Na+K+ Pump Passive movement of K+ across the membrane Passive movement of Na+ across the membrane Part B Resting membrane potential is approximately -70mV. Explain what resting membrane potential is and what -70mV refers to.