Q: Why do reactions like this require a polar protic solvent even though they mechanistically follow an…
A: Polar protic solvents are the solvents which have tendency to solvate a nucleophile with the help of…
Q: Which set of starting materials can be used to make the target molecule in one step? HO. Но Target…
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Q: Enolate Chemistry PS 2: Aldol Reactions B H. D Ph. H. Ph. H.
A:
Q: Which compound is the major product of the reaction sequence shown? (1) NANH,NH3, -35°C (2) CH3 CH2-…
A: 1) first reaction is acid base reaction. 2) second reaction is SN2 reaction 3) third reaction is…
Q: How do polar protic and aprotic solvents affect the reactivity of enolates ? 2.
A: Enolate ions Enolate formation can be depicted as; α H present near a carbonyl group is abstracted…
Q: Draw the major organic product of this E1 elimination reaction. Ignore byproducts. -Br 0.01 M NaOH…
A: This is a E1 reaction ,so at first step carbonation will be produced ,and in the second step base…
Q: t-BUOK E2 only Br
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Q: What is the major enolate formed in each reaction ?
A: For useful alkylation reactions of enolate anions, in the absence of other strong nucleophiles and…
Q: Draw the major organic product of the following reaction sequence. 1) NaH 2) A 3) H,0
A: Alcohols are weakly acidic in nature and it forms alkoxide ion in the presence of a base. The…
Q: Put the following leaving groups in order from best leaving group to worst leaving group: F Br I CI
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Q: Draw the organic products in each of the following reactions. OH PCC HO. CrO3 a. H2SO4, H20 OH OH…
A: Note: Since you have posted a question with multiple subparts, we will solve the first three…
Q: What is the final product of the following reaction sequence? 1. H2SO4 2. Br2, FeBr3 Br A C D Br Br…
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Q: 1.What is the best reagent to complete this synthesis? OA 1)???? CN 7.) NaCN.
A: Since you have posted a multiple questions in a single session, we are entitled to answer first…
Q: 2.) Draw the major product of the following reaction. Br
A: The ion is a very strong base and a very poor nucleophile because of the 3 bulky CH3 groups on the…
Q: Draw the major product of the three-step synthesis. 1. N. cat H3O* 2. Br 3. H30* ZI
A: ->Amine has nucleophilic character because it has loan pair hence it can give nucleophilic…
Q: Y. c) 2 eq. H20 .CI + b) Br d) Br Br Which pair of nucleophile and electrophile will react fastest…
A: To answer this question , we would first define SN2 reaction and a a bit about its mechanism.
Q: What is the major E2 elimination product formed from each alkyl halide?
A: The major E2 elimination product formed from given alkyl halide can be drawn as
Q: Which of the following anions is the best leaving group in an Sn1 reaction? а. F- b. Но- c. NH2- d.…
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Q: 9. Synthesis: complete the following transformation Br OCH3 b.
A: Applying concept of organic synthesis and reagent.
Q: Consider carbonyl compounds A– E attached below. Rank A–E in order of increasing amount of hydrate…
A: The amount of hydrate formed depends upon the electrophilic nature of carbonyl carbon. Higher the…
Q: 14. Why is the nitro group a meta director? A. Because it is sterically very large. B. Because it…
A: Since you have posted two different questions. According to guidelines I am solving 1st question.If…
Q: Explain why a Lewis acid is necessary in this aldol reaction. Include a structure formed by the…
A: Lewis acid Facilitate the attacking of nucleophile to the carbonyl carbon
Q: Draw the major organic product of the following reaction conditions. CH3 1. OsO4, H20 2. NalO4 ČH3
A: Organic reactions
Q: Draw the major organic product of the following reaction conditions. CH3 1. Os04, H20 2. NalO4 ČH3
A: Detail mechanistic pathway is given below to find out the major product
Q: Why does the leaving group rarely act as a base in SN1 reactions? The ABC step is exothermic and…
A: In a SN1 reaction the leaving group to leave it must be able to accept electron ,if a base remove…
Q: This reaction is an example of conjugate addition of a nucleophile to an a.B-unsaturated carbonyl.…
A: conjugate 1,4 addition is called Michael addition
Q: How can this product be synthesized via a Michael reaction.
A: Addition of active CH group at α,β-unsaturated carbonyl, cyano, ester, nitro compounds in basic…
Q: Draw the major organic product of the following reaction sequence. 1) RCO3H 2) MeMgBr 3) H20
A: The given reaction is the conversion of alkene to alcohol.
Q: 1) Listen Which reagent would best accomplish this transformation? OH JDHDMC OsO4 O Cro3 O KMNO4…
A: PCC will oxidise the alcohal into aldehyde
Q: HO-
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Q: Why is the nitro group a meta director? Select one: O a. Because it adds electron density to the…
A: 1. Nitro is electron withdrawing group. It will remove electron density from o, p positions.…
Q: How to synthesis compound 1 from compound 2? OMe t-Bu MeO2C MeO¿C но 1
A: For the synthesis of compound 1, the starting material, which is compound 2, is reduced selectively.…
Q: What reagent would you use to do this reaction? H2N HO. O a) HgSO4, H3o* b) KMNO4 O c) Cro3 d)…
A: KMnO4 strong oxidizing agent it cam oxidize almost all compounda even alkyl groupa to carbozylic…
Q: what is the major E1 product for the structure?
A: E1 reaction is based on the Zaitsev Rule which states that the most substituted alkene is the major…
Q: -CH3 CH,CH, —С—Ph
A: Michael addition is one of the common type of organic reaction which occurs between a carbonyl group…
Q: ? HO.
A: This is an example of the oxidation reaction with no change in the no. of carbon atom and the…
Q: Draw the major product of this E1 reaction. Ignore any inorganic byproducts. OH
A: Products are present on right hand side and reactants are present on left hand side in a reaction.
Q: Identify the reagent(s) needed for the following transformation: OH ?. + En 1. BH3 THF 2. H2O2, NAOH…
A: Given: Transformation of a reaction. To find : Best suitable reagents for the transformation.…
Q: Which halide is least reactive towards SN2 reactions ? O a. tert-butyl bromide O b. sec-butyl…
A: Sn2 reaction are bimolecular nucleophilic substitution reaction. This is single step reaction , and…
Q: CH3 DH H.
A: Since you have asked multiple question, we will solve the first question for you. If you want any…
Q: OH Pyridine (two equivalents)
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Q: HO OCH3 OCH3
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Q: What is the major Hofmann elimination product formed from attachedamine?
A: The given conformational isomer is staggered. The conformational isomers are the one which undergoes…
Q: What is one commonly used way to turn a poor leaving group into a good one?
A: Since you have posted multiple questions, we are entitled to answer the first only. Please repost…
Q: OH SOCI2 pyridine NaCN
A: SN2 reaction is a bimolecular nucleophilic substitution reaction which occurs in one step. Here the…
Q: Draw the major organic product of this E1 elimination reaction. Ignore byproducts. -OH H3O* heat…
A:
Q: ? Br
A:
Q: How to Converting an OH Group into a Better Leaving Group?
A: Alcohols are the organic compounds which contains an -OH group. This group is not a good leaving…
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The transition (to the right) is brought about by heating the starting material with a) Mg and anh. Ether b) KOH in alcohol c) H2O d) H3PO4
- Given that an E2 reaction proceeds with anti periplanar stereochemistry, draw the products of each elimination. The alkyl halides in (a) and (b) are diastereomers of each other. How are the products of these two reactions related? Recall from Section 3.2A that C6H5 −is a phenyl group, a benzene ring bonded to another group.Given that an E2 reaction proceeds with anti periplanar stereochemistry, draw the products of each elimination. The alkyl halides in (a) and (b) are diastereomers of each other. How are the products of these two reactions related? Recall from Section 3.2A that C6H5– is a phenyl group, a benzene ring bonded to another group.The 1,2‑dibromide is synthesized from an alkene starting material. Draw the alkene starting material. Clearly, show stereochemistry of the alkene.
- What other alkene is also formed along with Y in Sample Problem 9.3 (Attached) ? What alkenes would form from X if no carbocation rearrangement occurred?Carbocations often rearrange, as shown below. Draw in the hydrogens on the two carbons involved in the rearrangement, and show formal arrow-pushing to illustrate the transformation.The hydrobrominationof 2-methyl-1-butene could theoretically lead to 2 different alkyl bromides; in practice only one product is formed. Draw the structure of both theoretical products, circle the one that is actually produced, and briefly explain whyonly one product forms.
- The synthesis above can be performed with some combination of the reagents listed below. Give the necessary reagents in the correct order. Be sure to consider stereochemistry and regiochemistry.A. NaOHB. mCPBAC. OsO4, tBuOOHD. NaHE. H2, LindlarF. CH3CH2CH2BrG. CH3CH2ClH. NaNH2I. H3O+J. Na, NH3(l)Does cis- or trans-1-bromo-4-tert-butylcylohexane react faster in an E2reaction?Draw the mechanism ffrom benzaldehyde to this using: i)NaBH4 ii)TsCl, py iii)NaCN iiii)H+, H2O
- Rank the following carbocation in order of increasing stability?1. Which among these would be the most stable carbocation?a. Allylicb. Vinylicc. Primaryd. Secondary2. What is the primary reason for the stability of tertiary carbocations?a. Free rotationb. Resonancec. HyperconjugationTo make Halocyclopentane, what reagents and substartes are needed? Which one(below) is related with the Halocyclopentane? Esterification, Alcohol Halogenation ,Alkyl Halide Solvolysis, Alkene Hydration, Hydroboration, Alkene Bromination, Alkene Dihydroxylation, Epoxidation, Diels Alder, Aldol, Grignard Addition, Benzene Nitration, Friedel-Crafts, Carbonyl Reduction, Claisen Condensation, Alcohol Oxidation