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There are five substitution mutations in the dark-colored mutant Mc1r gene. Compare the DNA sequence of the light-colored wild-type Mc1r gene with the DNA sequence of the dark-colored mutant Mc1r gene. Indicate the locations of the five mutations by changing the font color to YELLOW for the five single DNA nucleotides that are mutated in the mutant Mc1r gene table.  Using the information in the introduction, determine whether each of these mutations is a silent, missense, or nonsense mutation. Using the mutant Mc1r gene data, fill in the columns (including DNA, mRNA, and amino acid) in gene table 2 that contain a silent mutation with BLUE. Likewise, fill in the columns that contain a missense mutation with RED. Shade any columns that contain nonsense mutations with GREEN. Then  Of the five mutations you identified in the mutant Mc1r gene, how many are:                  substitutions           insertions              deletions (Enter a number on each line.) 2. Of the five mutations you identified in the Mc1r gene, how many are:                  silent                         missense                      nonsense (Enter a number on each line.)

There are five substitution mutations in the dark-colored mutant Mc1r gene. Compare the DNA sequence of the light-colored wild-type Mc1r gene with the DNA sequence of the dark-colored mutant Mc1r gene. Indicate the locations of the five mutations by changing the font color to YELLOW for the five single DNA nucleotides that are mutated in the mutant Mc1r gene table.  Using the information in the introduction, determine whether each of these mutations is a silent, missense, or nonsense mutation. Using the mutant Mc1r gene data, fill in the columns (including DNA, mRNA, and amino acid) in gene table 2 that contain a silent mutation with BLUE. Likewise, fill in the columns that contain a missense mutation with RED. Shade any columns that contain nonsense mutations with GREEN. Then  Of the five mutations you identified in the mutant Mc1r gene, how many are:                  substitutions           insertions              deletions (Enter a number on each line.) 2. Of the five mutations you identified in the Mc1r gene, how many are:                  silent                         missense                      nonsense (Enter a number on each line.)

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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There are five substitution mutations in the dark-colored mutant Mc1r gene. Compare the DNA sequence of the light-colored wild-type Mc1r gene with the DNA sequence of the dark-colored mutant Mc1r gene. Indicate the locations of the five mutations by changing the font color to YELLOW for the five single DNA nucleotides that are mutated in the mutant Mc1r gene table.
 Using the information in the introduction, determine whether each of these mutations is a silent, missense, or nonsense mutation.

Using the mutant Mc1r gene data, fill in the columns (including DNA, mRNA, and amino acid) in gene table 2 that contain a silent mutation with BLUE.

Likewise, fill in the columns that contain a missense mutation with RED.

Shade any columns that contain nonsense mutations with GREEN.

Then 

  1. Of the five mutations you identified in the mutant Mc1r gene, how many are:

                 substitutions           insertions              deletions (Enter a number on each line.)

2. Of the five mutations you identified in the Mc1r gene, how many are: 

                silent                         missense                      nonsense (Enter a number on each line.)

 

GENE TABLE 2: (DARK COAT-COLOR PHENOTYPE) DNA mRNA Amino Acid DNA mRNA Amino Acid DNA DNA 015 mRNA Amino Acid CAA GUU 105 Valine Threonine CCG GGC 154 mRNA UUC Amino Phenylalani Acid ne AAG 230 TGT GCT ACA CGA GTG CAC TCG Glycine Histidine Serine Isoleucine AGC Serine ΝΑ mRNA Amino Acid CCA GGU GGG Arginine Glycine CCC Proline AGG ATA UAU UCC AUU 209 CGT GCA Alanine AAG Tyrosine Valine CCG UUC Phenylalani ne GGC TAA Glycine CAG GUC GUU TTA CGA AAU GCU Alanine AGG UCC Serine TGG ACC Valine Leucine GAC CUG GTG CCA CAC GGU CCG Glycine Valine GGC Threonine Leucine Glycine GAG CUC 212 GGU Glycine CAG GUC CAC GUG Valine Asparagine Histidine 112 TTA AAU CCA GGU Glycine Asparagine Proline AGG UCC 022 Serine TAA AUU Isoleucine GGG CCC 161 GAA CUU Leucine 237 GGA CCU Proline
Transcribed Image Text:GENE TABLE 2: (DARK COAT-COLOR PHENOTYPE) DNA mRNA Amino Acid DNA mRNA Amino Acid DNA DNA 015 mRNA Amino Acid CAA GUU 105 Valine Threonine CCG GGC 154 mRNA UUC Amino Phenylalani Acid ne AAG 230 TGT GCT ACA CGA GTG CAC TCG Glycine Histidine Serine Isoleucine AGC Serine ΝΑ mRNA Amino Acid CCA GGU GGG Arginine Glycine CCC Proline AGG ATA UAU UCC AUU 209 CGT GCA Alanine AAG Tyrosine Valine CCG UUC Phenylalani ne GGC TAA Glycine CAG GUC GUU TTA CGA AAU GCU Alanine AGG UCC Serine TGG ACC Valine Leucine GAC CUG GTG CCA CAC GGU CCG Glycine Valine GGC Threonine Leucine Glycine GAG CUC 212 GGU Glycine CAG GUC CAC GUG Valine Asparagine Histidine 112 TTA AAU CCA GGU Glycine Asparagine Proline AGG UCC 022 Serine TAA AUU Isoleucine GGG CCC 161 GAA CUU Leucine 237 GGA CCU Proline
GENE TABLE 1: (LIGHT COAT-COLOR PHENOTYPE) 015 DNA mRNA Amino Acid DNA mRNA Amino Acid DNA DNA CAA mRNA Amino Acid GUU 105 CCG GGC Valine Threonine Proline 154 mRNA UUC Amino Phenylalani Acid ne AAG 230 TGT GCT ACA CGA GTG CAC AUU Glycine Histidine Serine Isoleucine GCG CGC DNA mRNA Amino Acid GGG CCC CCC GGG Arginine Tyrosine Arginine Glycine AGG UCC ATA UAU 209 TGT ACA Threonine CCG AAG GGC UUC Phenylalani ne TAA CAG GUC CAA GUU CGA TTA GCU AAU Alanine AGC UCG Valine Threonine Serine TGG ACC GAC Valine Leucine CUG GTG CAC Glycine Asparagine Histidine TCA AGU Serine CCG GGC GAG CUC 212 CCA GGU Glycine Glycine Asparagine CAG CAC GUC GUG Valine Valine 112 TTA AAU CCA GGU AGG UCC 022 Leucine Glycine Leucine Serine TAA AUU Isoleucine GGG CCC Proline 161 GAA CUU 237 GGA CCU Proline
Transcribed Image Text:GENE TABLE 1: (LIGHT COAT-COLOR PHENOTYPE) 015 DNA mRNA Amino Acid DNA mRNA Amino Acid DNA DNA CAA mRNA Amino Acid GUU 105 CCG GGC Valine Threonine Proline 154 mRNA UUC Amino Phenylalani Acid ne AAG 230 TGT GCT ACA CGA GTG CAC AUU Glycine Histidine Serine Isoleucine GCG CGC DNA mRNA Amino Acid GGG CCC CCC GGG Arginine Tyrosine Arginine Glycine AGG UCC ATA UAU 209 TGT ACA Threonine CCG AAG GGC UUC Phenylalani ne TAA CAG GUC CAA GUU CGA TTA GCU AAU Alanine AGC UCG Valine Threonine Serine TGG ACC GAC Valine Leucine CUG GTG CAC Glycine Asparagine Histidine TCA AGU Serine CCG GGC GAG CUC 212 CCA GGU Glycine Glycine Asparagine CAG CAC GUC GUG Valine Valine 112 TTA AAU CCA GGU AGG UCC 022 Leucine Glycine Leucine Serine TAA AUU Isoleucine GGG CCC Proline 161 GAA CUU 237 GGA CCU Proline
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