There are two groups of drugs classified as antagonists of histamine receptor antagonists. The one group blocks activation of histamine, receptors, while the second group selectively blocks histamine, receptors. Mr HA is a pharmacy student who is worrying about his next pharmacology test, and he has come into the pharmacy complaining of stomach pain associated with gastric hyperacidity. 5.1. Identify the class of histamine antagonists that would be appropriate for Mr HA. Clearly motivate your choice by explaining the action of histamine at the specific receptor sub-type identified and thus the physiological outcome of using the appropriate histamine antagonist. 5.2. Several different local hormones and mediators play a role in platelet aggregation and blood coagulation. For each of the following mediators, identify (i) the site where the mediator is produced/found and (i) the physiological function when released 5.2.1. Thromboxane 5.2.2. Prostacyclin 5.2.3. Serotonin 5.2.4. Nitric oxide 5.3. Describe the synthesis pathway of the local hormone serotonin. Include all precursor chemicals, all enzymes involved, as welli the mechanisms by which serotonin's activity is terminated.

There are two groups of drugs classified as antagonists of histamine receptor antagonists. The one group blocks activation of histamine, receptors, while the second group selectively blocks histamine, receptors. Mr HA is a pharmacy student who is worrying about his next pharmacology test, and he has come into the pharmacy complaining of stomach pain associated with gastric hyperacidity. 5.1. Identify the class of histamine antagonists that would be appropriate for Mr HA. Clearly motivate your choice by explaining the action of histamine at the specific receptor sub-type identified and thus the physiological outcome of using the appropriate histamine antagonist. 5.2. Several different local hormones and mediators play a role in platelet aggregation and blood coagulation. For each of the following mediators, identify (i) the site where the mediator is produced/found and (i) the physiological function when released 5.2.1. Thromboxane 5.2.2. Prostacyclin 5.2.3. Serotonin 5.2.4. Nitric oxide 5.3. Describe the synthesis pathway of the local hormone serotonin. Include all precursor chemicals, all enzymes involved, as welli the mechanisms by which serotonin's activity is terminated.

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter19: The Peripheral Endocrine Glands

Section: Chapter Questions

Problem 2TAHL

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