This pedigree shows the inheritance of an autosomal dominant disorder. Il-1 and II-2 plan to have four children. What is the probability that 2 children will be affected and 2 will not? Hint: First find the probability that a child has the disease, then use the formula for binomial distribution. Success not affected. -pxqn-x P= I II n! (n-x)!x! 6/8 3/8 14/32 5/16 1/16 1 ? 2

This pedigree shows the inheritance of an autosomal dominant disorder. Il-1 and II-2 plan to have four children. What is the probability that 2 children will be affected and 2 will not? Hint: First find the probability that a child has the disease, then use the formula for binomial distribution. Success not affected. -pxqn-x P= I II n! (n-x)!x! 6/8 3/8 14/32 5/16 1/16 1 ? 2

Name: This pedigree shows the inheritance of an autosomal dominant disorder
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Description: This pedigree shows the inheritance of an autosomal dominant disorder. Il-1 and II-2 plan to havefour children. What is the probability that 2 children will be affected and 2 will not?Hint: First find the probability that a child has the disease, th

Human Biology (MindTap Course List)

11th Edition

ISBN:9781305112100

Author:Cecie Starr, Beverly McMillan

Publisher:Cecie Starr, Beverly McMillan

Chapter20: Chromosomes And Human Genetics

Section: Chapter Questions

Problem 7CT: The following pedigree shows the pattern of inheritance of red-green color blindness in a family....

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The following pedigree shows the pattern of inheritance of red-green color blindness in a family. Females are shown as circles and males as squares; the squares or circles of individuals affected by the trait are filled in black. What is the chance that a son of the third-generation female indicated by the arrow will be color blind if the father is not color blind? If he is color blind?
Does the phenotype indicated by the red circles and squares in this pedigree show an inheritance pattern that is autosomal dominant, autosomal recessive, or X-linked?
An allele responsible for Marfan syndrome Section 13.4 is inherited in an autosomal dominant pattern. What is the chance that a child will inherit the allele if one parent does not carry it and the other is heterozygous?
As it turned out, one of the tallest Potsdam Guards had an unquenchable attraction to short women. During his tenure as guard, he had numerous clandestine affairs. In each case, children resulted. Subsequently, some of the childrenwho had no way of knowing that they were relatedmarried and had children of their own. Assume that two pairs of genes determine height. The genotype of the 7-foot-tall Potsdam Guard was A9A9B9B9, and the genotype of all of his 5-foot clandestine lovers was AABB. An A9 or B9 allele in the offspring each adds 6 inches to the base height of 5 feet conferred by the AABB genotype. a. What were the genotypes and phenotypes of all the F1 children? b. Diagram the cross between the F1 offspring, and give all possible genotypes and phenotypes of the F2 progeny
Using the pedigree chart attached: Above is a pedigree for colorblindness. Based on the pedigree, is the disease dominant or recessive and is it sex-linked or autosomal? Why? Furthermore, what is the probability that 18 on this chart is affected but the condition, and what is the probability that 18 is a carrier? Why? Are the probability of being a carrier and an affected individual different? Why?
The attached image is a pedigree of a family with a history of sickle cell anemia (the individuals with the filled-in symbols have the disease and no new mutations are occurring in any individual). Sickle cell anemia is inherited in an autosomal recessive manner. What is the probability that the individual with the question mark (?) will get the disease? a) 1/4 b) 1/2 c) 2/3 d) 1
Using the pedigree, assume that the disease is caused by an autosomal dominant allele, R. Give the genotype of the following individuals: (a) III-4 (the girl at lower right) (b) II-3 (the girl’s mother) (c) II-4 (the girl’s father)
What are the genotypes of the mother and father in the pedigree below? The pedigree shows albinism (an autosomal recessive trait). The shaded shapes represent albino individuals. a. mother - homozygous dominant; father - homozygous dominant b. mother - heterozygous; father - homozygous recessive c. mother - homozygous recessive; father - heterozygous d. mother - heterozygous; father - heterozygous e. mother - homozygous dominant; father - homozygous recessive
Ann's family has a history of cystic fibrosis, a recessive genetic disease. In the pedigree, family members who are afflicted with the disease are shown in red. Members who are unafflicted may or may not be carriers. Which of the given family members can be identified definitively as unafflicted carriers of cystic fibrosis?
Above is a pedigree for colorblindness. Based on the pedigree, is the disease dominant or recessive and is it sex-linked or autosomal? Why? Furthermore, what is the probability that 18 on this chart is affected but the condition, and what is the probability that 18 is a carrier? Why? Are the probability of being a carrier and an affected individual different? Why
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The following pedigree shows the inheritance of Huntington’s disease, a fatal genetic disorder that causes neurodegeneration. Since signs and symptoms usually do not appear until adulthood, many who are carriers may not realize their risk of passing on the disease-causing allele. The following pedigree represents a family in which some people are affected by Huntington’s disease. Using just the information on this pedigree, is Huntington’s disease caused by a dominant allele or recessive alleles? What are the genotypes of the grandparents (I-1 and I-2)? What are the genotypes of the parents (II-6 and II-7)? If the parents above have another child, what is the chance that they will be affected by the Hungtington’s disease allele? What are the genotypes of the unaffected children (III-8, 9, 10)? What is the chance that the unaffected children above will pass on a Huntington’s disease allele to their children? What is the genotype of the affected child (III-11)? What is the chance…