TLC was used to compare the solubility of two compounds A and B in a solvent system (acetic acid, methanol, H2O). The distances that solvent has moved in the silica gel TLC was 12 cm. and for the compounds were 2 and 8 cm respectively. (a) Calculate the Rf values and which compound is more soluble and which one is more polar. (b) What are the factors affecting the Rf value

Principles of Instrumental Analysis
7th Edition
ISBN:9781305577213
Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Chapter28: High-performance Liquid Chromatography
Section: Chapter Questions
Problem 28.3QAP
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TLC was used to compare the solubility of two compounds A and B in a solvent 
system (acetic acid, methanol, H2O). The distances that solvent has moved in the 
silica gel TLC was 12 cm. and for the compounds were 2 and 8 cm respectively. 
(a) Calculate the Rf values and which compound is more soluble and which one is 
more polar. (b) What are the factors affecting the Rf value

 

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