Using the information below, what is the appropriate statistical test to employ? You intend to understand if the miRNA biomarker (miR-16) level is significantly different between normal and breast cancer (BC) patients.
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Using the information below, what is the appropriate statistical test to employ?
You intend to understand if the miRNA biomarker (miR-16) level is significantly different between normal and breast cancer (BC) patients.
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- Measles is a highly contagious infection of the respiratory system and is caused by a virus. Despite the fact that more than 80% of the world’s population is vaccinated for it, measles remains the fifth leading cause of death worldwide. In general, the term pathogenesis refers to the way a disease originates and develops over time. In the case of measles, the virus enters through the respiratory tract and replicates there before spreading into the bloodstream and then the skin. Figure 1: Shown is a transmission electron micrograph of a measles virus. The measles pathogenesis function used to model the development of the disease is given by the following equation: f (t) = −t (t − 21) (t + 1) Where t is measured in days and f (t) represents the number of infected cells per millilitre [mL] of plasma. What is the peak infection time for the measles virus? Solve the above problem through the following steps: (a) Expand equation 2 fully. (b) Calculate the first derivative f′ (t), of the…Measles is a highly contagious infection of the respiratory system and is caused by a virus. Despite the fact that more than 80% of the world’s population is vaccinated for it, measles remains the fifth leading cause of death worldwide. In general, the term pathogenesis refers to the way a disease originates and develops over time. In the case of measles, the virus enters through the respiratory tract and replicates there before spreading into the bloodstream and then the skin.Figure 1: Shown is a transmission electron micrograph of a measles virus.1The measles pathogenesis function used to model the development of the disease is given by the following equation: f (t) = −t(t − 21)(t + 1) (2)where t is measured in days and f (t) represents the number of infected cells per milliliter [mL] of plasma. What is the peak infection time for the measles virus? Solve the above problem through the following steps:(a) Expand equation 2 fully. [1] (b) Calculate the first derivative f′ (t), of the…Measles is a highly contagious infection of the respiratory system and is caused by a virus. Despite the fact that more than 80% of the world’s population is vaccinated for it, measles remains the fifth leading cause of death worldwide. In general, the term pathogenesis refers to the way a disease originates and develops over time. In the case of measles, the virus enters through the respiratory tract and replicates there before spreading into the bloodstream and then the skin.The measles pathogenesis function used to model the development of the disease is given by the following equation: f (t) = −t (t − 21) (t + 1) Where t is measured in days and f (t) represents the number of infected cells per millilitre [mL] of plasma. What is the peak infection time for the measles virus? Solve the above problem through the following steps: (a)Expand equation f (t) = −t (t − 21) (t + 1) in fully. (b) Calculate the first derivative f′ (t), of the equation found in part (a). (c) Find the…
- Omega-3, finis Exercises 21 and 23 describe an experi-ment investigating the effectiveness of omega-3 fats in treating bipolar disorder. Suppose some of the 30 sub-jects were very active people who walked a lot or got vig-orous exercise several times a week, while others tended to be more sedentary, working office jobs and watchinga lot of TV. Why might researchers choose to block thesubjects by activity level before randomly assigning themto the omega-3 and placebo groups?AVONEX and MS. An issue of Inside MS contained an article describing AVONEX (interferon beta-1a), a drug used in the treatment of relapsing forms of multiple sclerosis (MS). Included in the article was a report on “. . . adverse events and selected laboratory abnormalities that occurred at an incidence of 2% or more among the 158 multiple sclerosis patients treated with 30 mcg of AVONEX once weekly by IM injection.” In the study, 158 patients took AVONEX and 143 patients were given placebo. a. Is this study observational or is it a designed experiment?b. Identify the treatment group, control group, and treatmentsA mutation in Gene A is thought to be associated with a disease. The mutation in Gene A is found in 5% of the population. 2% of the whole population is diagnosed with disease B at some point in their life time. 1% of the population both has the mutation and also gets diagnosed with the disease in their life time. Is the provided data adequate to test the independency of mutation in Gene A and occurrence of Disease B? If it is not, what other information or data is needed to test the independency? What is the probability of Disease B, among the individuals with the mutation in Gene A? What is the probability of having the mutation in Gene A among the individuals with Disease B? If an individual has the mutated Gene A, what is their Relative Risk of developing the disease?
- A company utilizes two different machines to manufacture parts of a certain type. During a single shift, a sample of n = 20 parts produced by each machine is obtained, and the value of a particular critical dimension for each part is determined. The comparative boxplot at the bottom of this page is constructed from the resulting data. Compare and contrast the two samples.Comparative boxplot for Exercise 58.Recently there have been concerns about the effects of phthalates on the devel- opment of the male reproductive system. Phthalates are common ingredients in many plastics. In a pilot study a researcher gave pregnant rats daily doses of 750 mg/kg of body weight of DEHP (di-2-ethylhexyl phthalate) throughout the period when their pups’ sexual organs were developing. The newly born male rat pups were sacrificed and their seminal vesicles were dissected and weighed. Below are the weights for the eight males (in mg). 1710 1630 1580 1670 1350 1650 1600 1650 If untreated newborn males have a mean of 1700 mg, can you say that rats exposed to DHEP in utero have a significantly lower weight?please help me out. show full working out for better understanding Hereditary hemochromatosis (HH) is a recessively inherited genetic disorder resulting from mutations in the HFE gene. There are several possible mutations of different degrees of importance but the disease expresses itself only when at least 2 arepresent in any one individual. A blood analysis was performed on 3,000 blood samples from newborn babies of Caucasian descent in the state of Michigan, USA. The results showed that 163 of those sampled carried two mutations in the HFE gene. a. What is the proportion in the sample that carry the two mutations of the HFE gene? b. Calculate the 95% confidence interval for the proportion of this population that carries two mutations in the HFE Check the data for the necessary conditions and show full working. c. Interpret your interval in context d. If the researcher wanted to halve (x ½) the margin of error in the confidence interval found, what sample size would be required…
- The germination rate of seeds is defined as the proportion of seeds that, when properly planted and watered, sprout and grow. A certain variety of grass seed usually has a germination rate of 0.80, and a company wants to see if spraying the seeds with a chemical that is known to change germination rates in other species will change the germination rate of this grass species. (a) Suppose the company plans to spray a random sample of 400 seeds and conduct a two-sided test of 0: 0.8Hpusing = 0.05. They determine that the power of this test against the alternative 0.75pis 0.69. Interpret the power of this test.(b) Describe two ways the company can increase the power of the test. What is a disadvantage of each of these ways? (c) The company researchers spray 400 seeds with the chemical and 307 of the seeds germinate. This produces a 95% confidence interval for the proportion of seeds that germinate of (0.726, 0.809). Use this confidence interval to determine whether the test described in…# TODO 2: Use the Matplotlib plt.hist() method to display area values. All we have to do is supply area_values to the plt.hist() method, and it will compute the bins for us. # TODO 2 plt.show() Expected Output:The average drying time of a manufacturer’s paint is 20 minutes. Investigating the effectiveness of a modifica-tion in the chemical composition of her paint, the manu-facturer wants to test the null hypothesis μ = 20 minutes against a suitable alternative, where μ is the average dry-ing time of the modified paint. (a) What alternative hypothesis should the manufactureruse if she does not want to make the modification in thechemical composition of the paint unless it decreases thedrying time?(b) What alternative hypothesis should the manufactureruse if the new process is actually cheaper and she wants tomake the modification unless it increases the drying timeof the paint?