Using the information below, what is the appropriate statistical test to employ? You intend to understand if the miRNA biomarker (miR-16) level is significantly different between normal and breast cancer (BC) patients.

Linear Algebra: A Modern Introduction
4th Edition
ISBN:9781285463247
Author:David Poole
Publisher:David Poole
Chapter4: Eigenvalues And Eigenvectors
Section4.6: Applications And The Perron-frobenius Theorem
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Using the information below, what is the appropriate statistical test to employ?

You intend to understand if the miRNA biomarker (miR-16) level is significantly different between normal and breast cancer (BC) patients.

A
plasma miR-16 level
(Normalized to U6)
C
plasma miR-451 level
(Normalized to U6)
100000-
10000-
1000-
100-
10-
1-
0.1-
1000000
100000-
10000-
1000-
100-
FOL
10-
1
p < 0.0001
Normal
(n=100)
Normal
(n=100)
p < 0.0001
H-
BC
(n=120)
BC
(n=120)
B
plasma miR-21 level
(Normalized to U6)
D
plasma miR-145 level
(Normalized to U6)
10000
1000-
100-
10-
0.1-
100-
10-
0.1-
0.01
Normal
(n=100)
H:
p < 0.0001
Normal
(n=100)
p < 0.05
d
HH₂
BC
(n=120)
++
BC
(n=120)
Transcribed Image Text:A plasma miR-16 level (Normalized to U6) C plasma miR-451 level (Normalized to U6) 100000- 10000- 1000- 100- 10- 1- 0.1- 1000000 100000- 10000- 1000- 100- FOL 10- 1 p < 0.0001 Normal (n=100) Normal (n=100) p < 0.0001 H- BC (n=120) BC (n=120) B plasma miR-21 level (Normalized to U6) D plasma miR-145 level (Normalized to U6) 10000 1000- 100- 10- 0.1- 100- 10- 0.1- 0.01 Normal (n=100) H: p < 0.0001 Normal (n=100) p < 0.05 d HH₂ BC (n=120) ++ BC (n=120)
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