Using this information and the image provided, describe the reaction catalyzed by an esterase and classify it as one of the 6 classes of enzymes. The insert also tells you that Enalaprilat (the active form of Enalapril) targets angiotensin-converting enzyme (ACE), which cleaves the blood-pressure regulating peptide angiotensin I. The active form of the drug looks very similar to the endogenous substrate of the enzyme ACE. Based on this information, what type of interaction is occurring between Enalaprilat and ACE? Propose how the presence of Enalaprilat changes the overall reaction.
Carbohydrates
Carbohydrates are the organic compounds that are obtained in foods and living matters in the shape of sugars, cellulose, and starch. The general formula of carbohydrates is Cn(H2O)2. The ratio of H and O present in carbohydrates is identical to water.
Starch
Starch is a polysaccharide carbohydrate that belongs to the category of polysaccharide carbohydrates.
Mutarotation
The rotation of a particular structure of the chiral compound because of the epimerization is called mutarotation. It is the repercussion of the ring chain tautomerism. In terms of glucose, this can be defined as the modification in the equilibrium of the α- and β- glucose anomers upon its dissolution in the solvent water. This process is usually seen in the chemistry of carbohydrates.
L Sugar
A chemical compound that is represented with a molecular formula C6H12O6 is called L-(-) sugar. At the carbon’s 5th position, the hydroxyl group is placed to the compound’s left and therefore the sugar is represented as L(-)-sugar. It is capable of rotating the polarized light’s plane in the direction anticlockwise. L isomers are one of the 2 isomers formed by the configurational stereochemistry of the carbohydrates.
- Using this information and the image provided, describe the reaction catalyzed by an esterase and classify it as one of the 6 classes of enzymes.
- The insert also tells you that Enalaprilat (the active form of Enalapril) targets angiotensin-converting enzyme (ACE), which cleaves the blood-pressure regulating peptide angiotensin I. The active form of the drug looks very similar to the endogenous substrate of the enzyme ACE. Based on this information, what type of interaction is occurring between Enalaprilat and ACE? Propose how the presence of Enalaprilat changes the overall reaction.
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