Watson and Crick used scientific reasoning, their knowledge of biochemistry, and the research of other scientists to make one of the most important scientific claims of their time: DNA is a double helix with strands running in opposite directions. Between these strands, A pairs with T, and C pairs with G.

Watson and Crick used scientific reasoning, their knowledge of biochemistry, and the research of other scientists to make one of the most important scientific claims of their time: DNA is a double helix with strands running in opposite directions. Between these strands, A pairs with T, and C pairs with G.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter8: The Structure, Replication, And Chromosomal Organization Of Dna

Section: Chapter Questions

Problem 13QP

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In the concluding statement of Watson and Crick's seminal paper introducing the atomic structureof DNA, they write,"It has not escaped our notice that the specific pairing we have postulatedmediately suggests a possible copying mecha the genetic material (Watson, JDCrick, 1953)" Some consider this one of the biggest understatements in modern biology, butWatson and Crick couldn't confirm the mechanism for copying DNA because of lack of hardevidence. The scientists were racing to publish ahead of their competitors, so they included thestatement to be able to introduce the model before proof was available. The base-pairing inherentto the structure of DNA certainly strongly suggested a mechanism for creating an identical copy ofthe DNA, but it wasn't proven until Meselson and Stahl (1958) carried out their classic study. Notonly was this a landmark experiment for the essential process it helped to define, but it was alsorecognized for its elegant simplicityFor these reasons. Meselson and…
Which of the following is true about the structure of DNA as proposed by Watson and Crick (B-form DNA)? A. DNA forms a left-handed double helix. B. The strands of DNA are parallel. C. The complementary base pairs are held together by hydrogen bonds. D. A complete turn of the double helix occurs after every base pair.
While trying to determine the structure of DNA, Watson and Crick at one point proposed that like bases are bonded to like bases. For example, thymine would be bonded to thymine, cytosine would be bonded to cytosine, and so on. Explain why this proposed model would not fit based on what was discovered to be true about DNA.
How did Griffiths and Avery discover that DNA was the molecule of heredity? Would we have been able to discover the structure of DNA without this work? Why or why not? Would we have been able to understand or actually try to understand DNA replication without his work? Why or why not?
These are concerned with the replication and synthesis ofDNA. Write a short essay that distinguishes between the termsreplication and synthesis, as applied to DNA. Which of the two ismost closely allied with the field of biochemistry?
Watson and Crick were the first to __. Discover DNA's double helical structureDiscover DNAisolate DNAbuild the first DNA modelclone DNA
Let’s suppose you have recently identified an organism that wasscraped from an asteroid that hit the earth. (Fortunately, no onewas injured.) When you analyze this organism, you discover thatits DNA is a triple helix, composed of six different nucleotides: A,T, G, C, X, and Y. You analyze the composition of the DNA andfind the following amounts of the six bases: A = 24%, T = 23%,G = 11%, C = 12%, X = 21%, Y = 9%. What rules would you proposethat govern triplex-DNA formation in this organism? Note: There is more than one possibility.
You have a sample of genetic material. The nitrogenous base content is 29% guanine. a) If the sample is DNA, what are the amounts of the other bases? Explain your thought process b) Why can you not determine the amounts of the other bases if the sample is RNA? Explain your answer c) How did Watson and Crick make use the relationships between base pairs as they constructed the model for DNA?
What was the contribution of Rosalind Franklin to the discovery of DNA's structure? a.Discovery that in DNA the amounts of adenine and thymine were identical as were the amounts of guanine and cytosine b.Theoretical model of DNA's structure and the pairing of nitrogenous bases c. X-ray diffraction images of DNA that showed that DNA had two chains twisted into a double helix with a backbone containing phosphate groups on the outside and bases on the inside
Nucleic acids: features of structural organization, biologicalfunctions of DNA and RNA. Experimental proof of the geneticrole of DNA (phenomenon of transformation)
Chargaff determined the base composition of DNA from a variety ofdifferent sources.What information do you know based onthe question and based on your understanding of thetopic?.
Describe why the structure of DNA led Watson and Crick to point out “apossible copying mechanism for the genetic material.”