What causes most of the phenotypic abnormalities in someone with Down's Syndrome? A) They have many gene mutations that produce nonfunctional proteins. B) They express too much of some proteins during development. C) Their cells cannot go through mitosis properly during development because they have an odd number of chromosomes. D) Their chromosomes cannot pair during meiosis.

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations
Section: Chapter Questions
Problem 7QP: What chromosomal abnormality can result from dispermy?
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What causes most of the phenotypic abnormalities in someone with Down's Syndrome?

A) They have many gene mutations that produce nonfunctional proteins.

B) They express too much of some proteins during development.

C) Their cells cannot go through mitosis properly during development because they have an odd number of chromosomes.

D) Their chromosomes cannot pair during meiosis.

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