What is nondisjunction? Why does it cause chromosomal abnormalities? What is aneulploidy? Trisomy?  Monosomy? Which kind of monosomy always results in miscarriage in early pregnancy?     What do these terms mean:  genotype, phenotype, allele, homozygous, heterozygous?  Be able to recognize single gene inheritance patterns [autosomal dominant, autosomal recessive, X linked recessive] from a pedigree.  Also, how are simple Mendelian traits transmitted? What genotype  produces the phenotype?  Why do some inheritance patterns result in many more males than females  showing the phenotype?    What inheritance patterns do Huntington disease and sickle cell anemia, and hemophilia follow (autosomal dominant or autosomal recessive, or X-linked recessive)? What are some of the symptoms of  these diseases?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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 What is nondisjunction? Why does it cause chromosomal abnormalities? What is aneulploidy? Trisomy?  Monosomy? Which kind of monosomy always results in miscarriage in early pregnancy?    

  • What do these terms mean:  genotype, phenotype, allele, homozygous, heterozygous? 
  • Be able to recognize single gene inheritance patterns [autosomal dominant, autosomal recessive, X linked recessive] from a pedigree.  Also, how are simple Mendelian traits transmitted? What genotype  produces the phenotype?  Why do some inheritance patterns result in many more males than females  showing the phenotype?   
  • What inheritance patterns do Huntington disease and sickle cell anemia, and hemophilia follow (autosomal dominant or autosomal recessive, or X-linked recessive)? What are some of the symptoms of  these diseases? 
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