What is the best set of conditions to convert an appropriate dihalide into a terminal alkyne? 1. 1 equivalent of NaNH2 2. 2 equivalents of NaOH 3. 2 equivalents of NaNH2 4. 3 equivalents of NaNH2, then quench with H3O+

What is the best set of conditions to convert an appropriate dihalide into a terminal alkyne? 1. 1 equivalent of NaNH2 2. 2 equivalents of NaOH 3. 2 equivalents of NaNH2 4. 3 equivalents of NaNH2, then quench with H3O+

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter19: Eas: Electrophilic Aromatic Substitution

Section: Chapter Questions

Problem 7E: When toluene is treated with sulfuric and nitric acids under special conditions, three nitro (NO2)...

See similar textbooks

Related questions

Q: Which is the correct depiction of the electron transfer of Na and Cl? No of the choices .Na. Na •…

A: For subpart one, we have the atoms Na and Cl undergoing formation of NaCl , we need to write the…

Q: Is the reaction for the formation of methanol exothermic or endothermic? One sentence only

A: The reaction for the formation of methanol is exothermic.

Q: b. tBuO₂C roa + & co Hint: Cs₂CO3 is a base. CO₂Me CS₂CO3 " tBuO₂C O HO CO₂Me

A: Given,The reaction is:

Q: Devise a route to convert propene to propanone. Specify, in order, the reagents you would use. The…

A: The question is based on the concept of organic synthesis.We need to synthesize the product using…

Q: Calculate the mass of methanol when burned in oxygen (assuming complete combustion), required to…

A: Information of question

Q: 1. For the reaction scheme of the hydroboration step of 1-hexene. BH 3 THF BH₂ BH₂ a. Draw the…

A: Boranes are electron deficient species, they are devoid of octet. So boranes have the tendency to…

Q: e. CH3CHCH,CH2-C—H IUPAC name: IUPAC name: CO CH3

A: Two questions based on the nomenclature of organic compounds. One compound is ketone while the other…

Q: Question 2 edi Which element is reduced in the following reaction? 6H₂0 Fe2S3 + 12HNO3→2Fe (NO3)3 +…

A: Answer:

Q: Draw the structure of the expected product of this reaction series. 1) NaOCH3/CH3OH 2) 3) H30Ⓡ H ↑…

A: In the first step, presence of base, it abstract acidic alpha proton and form enolate ion, which act…

Q: e) f) f) OH CH3CH₂ONa Br CH₂CH₂OH CH,CH,ONa

A: An arrow always depicts from a region of high electron density to low electron density ; that is…

Q: Write the systematic name of each organic molecule: structure CI name 0 0 X Ś

Q: Determine whether the following molecule is chiralis chiral, drawi is not chiral, draw a stere

A: The given organic compound is (1 R, 2 R)-1,2-dimethylcyclopentane.We have to identify whether this…

Q: What classification of reaction is shown? a Select an answer and submit. For keyboard navigation,…

A: Answer:Substitution reaction: It is a type of reaction in which one atom or group in the substrate…

Q: A common alkene starting material is shown below. Predict the major product or missing reagent to…

A: Alkene reacts with hydrogen halide according to Markovnikov rule to form alkyl halide.Alkene reacts…

Q: alkane P. 0 1. Br2/light 2. 1 equiv. KOtBu 3. BH3 4. H₂O2/NaOH 5. PCC of O. Sn ?

A: Alkane is saturated hydrocarbon Find out intermediate and product of reaction

Q: Draw the predominant product(s) of the following reactions including stereochemistry when it is…

A: The above reaction is the Hydrohalogenation reaction.In this Reaction Alkyne reacts with the HI (…

Q: Question 13 of 15 ● Submit Determine the equilibrium constant for a reaction at 380.0 K if AG° =…

Q: 21.2 mL of 0.147 M solution of hydrochloric acid is titrated with 0.112 M NaOH solution. What is…

A: Given data isMolarity of HCl = 0.147 MVolume of HCl = 21.2 mLMolarity of NaOH = 0.112 MVolume of…

Q: c) Oxidation of 3-ethyl-5-methylheptanal d) Neutralization of 3,N-dimethyl-1-butanamine with HBr

A: Oxidation - Addition of oxygen or removal of hydrogen. Neutalization reaction - The reaction between…

Q: Predict the major product(s) of the following reaction. For all reactions that are not…

A: An arrow always depicts from a region of high electron density to low electron density ; that is…

Q: Consider the following reaction at equilibrium: Cl2(g) + 3 F2(g) ⇌ 2 ClF3(g) If the concentration of…

A: The objective of the question is to understand the effect of a change in concentration of one of the…

Q: For each atom in the table below, write down the subshell from which an electron would have to be…

A: The objective of the question is to write down the subshell from which an electron would have to be…

Q: Draw the Lewis structures for three resonance forms of the nitrate ion, NO3. Include electron lone…

A: Lewis structure is a method of representing bonding pattern in a molecule.It tells us how different…

Q: Each of the insoluble salts below are put into 0.10 M hydrochloric acid solution. Do you expect…

A: The question is based on the concept of chemical equilibrium.We need to identify the solubility of…

Q: Suppose the molecule in the drawing area below were subjected to mildly oxidizing reaction…

A: Given is monosaccharide molecule. Monosaccharides are the simplest carbohydrates and cannot be…

Q: 07 Question Draw the resulting product(s) from the coupling of the given radicals. Inlcude all…

A: Radical reaction occurs either through the stable radical formation by rearrangement or by the…

Q: Write down a balanced chemical equation for the complete combustion of methanol CH3OH(I) to CO2(g)…

A: In combustion reaction, an organic compound is burned in oxygen to form carbon dioxide and…

Q: 1. Predict the products and draw a detailed mechanism for the following two reactions a) b) d +HBr…

A: Addition of HBr in alkene is according to markovnikov's rule where more substituted alkyl halide is…

Q: Select the major and minor product(s) of the following reaction. If only one product is formed…

A: Given Select the major and minor products.

Q: Construct the expression for Kc for the following reaction. C(s) + H,O(g) = CO(g) + H,(g) Drag the…

A: Equilibrium constant is defined as the ratio of concentration of products to the concentration of…

Q: Complete and balance the following half-reaction in basic solution. Be sure to include the proper…

Q: Ag2CO3(s) Ag (aq) CO32-(aq) O-4.8 Calculate the standard change in entropy (AS) when 1 mole of…

A: Entropy is a measure of the randomness of the system. The entropy change in a chemical reaction can…

Q: Acid hydrolysis of the following molecule yield the given product. O O True O False H3O* heat HO OH

A: The ester in the presence of acid undergoes a hydrolysis reaction to produce a carboxylic acid and…

Q: a. A student massed out 0.175 g of an unknown diprotic acid on an analytical balance, and then…

A: Note: Since you have posted a question with multiple sub-parts, we will provide the solution only to…

Q: Name the following alkenes.

A: A question based on the nomenclature of organic compounds. For the given alkene the respective IUPAC…

Q: Problem 20 of 50 H₂C H Select to Add Arrows H Select to Add Arrows Submit

A: Given is carbanion molecule.Carbanion is species in which carbon carries negative charge.Curved…

Q: Consider these compounds: A. NICO3 B. Zn(OH)2 C. Cus D. Fe(OH) 2 Complete the following statements…

A: Answer:Ionic compound that has low solubility in water is called as sparingly soluble compound and…

Q: 0 Indicate the product of the reaction outlined in the scheme above. OH HO OH of NaBH₁ No reaction

A: NaBH4 is a mild reducing agent that can reduce a ketone to a secondary alcohol and an aldehyde to a…

Q: LL 1) KBr 2) CH3CO₂Li

A: The question is based on organic reactions.We need to identify the product and explain its…

Q: I. Contestar las preguntas A-C con respecto a la siguiente reacción (requiere más de un paso) & = d…

A: First step of this convertion=>Girgnard reagent is used.first nucleophilic attack then…

Q: Which of the indicated protons in the following compound would appear farthest upfield in the ¹H NMR…

A: NMR spectroscopy is a very important tool for the determination of the structure of the organic…

Q: Draw the product of this reaction. Ignore inorganic byproducts. KOH CHCI 3 Drawing Q

A: Given,The reaction:

Q: Mono-chlorination of n-butane yields 1-chlorobutane (30%) and 2- chlorobutane (70%). If each C-H…

A: Mono-chlorination of n-butane yields 1-chlorobutane (30%) and 2-chlorobutane(70%) .Here, product…

Q: Based on IR absorbances, rank the following C-O bonds in order of increasing bod strengths: H (A) OH…

A: This stretching frequency depends on the strength of the bond which is governed by Hooke's law.This…

Q: 2-methyl-2-pentanol Draw the structure of the alkene that was used to prepare the alcohol in highest…

A: A question based on reactions of alkenes. Name of an alcohol product is given that is to be matched…

Q: Devise a route to carry out the following conversion: a. SOCI₂, pyridine (Specify the reagents you…

A: The question is based on the concept of organic synthesis.We need to synthesize the product using…

Q: Br $ H R Br H H₂C • S Br H OH tax T o(-)(+)Na W X ene Y, the configuration of which is: a, Z; b, E,…

A: Given are organic compounds.Given is alkene Y which is cis alkene and has configuration Z.

Q: Draw the starting structure that would lead to this polymer under radical conditions. Drawing A or…

A: Given a polymer product, radical initiator AIBN.

Q: ← Problem 3 of 24 Draw the product of the reaction shown below. Ignore inorganic byproducts. cat.…

A: This is an example of nitration reaction. It involves aromatic electrophilic substitution reaction.

Q: What is the energy in kj/mol of UV radiation with a wavelength of 400 nm

A: Wavelength of UV radiation = 400 nm To determine: Energy of radiation 1 nm = 10-9 m

Concept explainers

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.

Question

What is the best set of conditions to convert an appropriate dihalide into a terminal alkyne?

1. 1 equivalent of NaNH₂

2. 2 equivalents of NaOH

3. 2 equivalents of NaNH₂

4. 3 equivalents of NaNH₂, then quench with H₃O⁺

(The third option is not the correct answer.)

Definition Definition Organic compounds that contain at least one triple bond between carbon-carbon atoms. The general molecular formula for alkynes with one triple bond is C n H 2n-2 .

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1: Basic discussion

VIEW

Step 2: Mechanism of reaction

VIEW

Solution

VIEW

Step by step

Solved in 3 steps with 3 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

When toluene is treated with sulfuric and nitric acids under special conditions, three nitro (NO2) groups are substituted for hydrogens at the 2, 4 and 6 positions on the ring (the next section discusses why the 2, 4, and 6 positions are substituted). The product is a highly explosive substance called 2,4,6-trinitrotoluene. This subastance is commonly known by a three letter name. What is it?
An SN2 mechanism takes place when 3-(bromomethyl)pentane is added to each nucleophile listed below. Which nucleophile will also require an acid-base step after the substitution step in order to produce a neutral (not charged) product? A. LiN(CH3)2 B. NaI C. KN3 D. HSCH3 (Please type answer no write by hend)
Choose the correct answer on the following questions: Zaitsev’s rule states that: the alkene with less alkyl substituents is the major product in base-induced elimination reactions the more highly substituted carbocation is formed as the intermediate rather than the less highly substituted one the alkene with more alkyl substituents is the major product in base-induced elimination reactions the less highly substituted carbocation is formed as the intermediate rather than the more highly substituted one Markovnikov rule states that: the alkene with less alkyl substituents is the major product in base-induced elimination reactions the more highly substituted carbocation is formed as the intermediate rather than the less highly substituted one the alkene with more alkyl substituents is the major product in base-induced elimination reactions the less highly substituted carbocation is formed as the intermediate rather than the more highly substituted one The Hoffman rule states that:…
The product of the second synthetic step undergoes tautomerization in aqueous medium to form the final product. Draw the structures for both of these products. 1. Draw the product of the oxidation of the organoborane formed in Step 1. Include lone pairs and nonzero formal charges. 2. Draw the more stable tautomer that is the final product. Include lone pairs and nonzero formal charges.
Choose the appropriate reagent for the following reaction. A) TsCl/pyridine B) SOCl2/pyridine C) ZnCl2 D) PBr3 E) HI
Please answer this NEATLY, COMPLETELY, and CORRECTLY for an UPVOTE. Which of the following reagent reacts with an alkene that will yield an anti- or non-Markovnikov addition product? (A) H2O/H+ (B) HBr (C) HCl (D) [1] HX, ROOR', UV light
What is the rate law implied by the mechanism given below? CH3COCH3(aq) + H+(aq) ←→ CH3C(OH)CH3+(aq) (fast, reversible) CH3C(OH)CH3+(aq) → CH3C(OH)=CH2(aq) + H+(aq) (slow) CH3C(OH)=CH2(aq) + Br2(aq) → CH3C(OH)CH2Br+(aq) + Br-(aq) (fast) CH3C(OH)CH2Br+(aq) → CH3COCH2Br(aq) + H+(aq) (fast) A. Rate = k[CH3COCH3][H+] B. Rate = k[CH3COCH3] C. Rate = k[CH3COCH3][Br2] D. Rate = k[CH3COCH3]2 E. Rate = k[CH3COCH3][Br2]/[H+] (Answer is A, looking for explanation why!).
The expected major product from the treatment of 1-pentyne with 1 equivalent of HBr is: 1,2-dibromopentane 1-bromo-1-pentene 2-bromo-1-pentene 1,1-dibromopentane 2,2-dibromopentane
1. What type of reaction is occuring in step 3? (halogenation, hydrohalogenation, reduction, keto–enol tautomerism, dehydrohalogenation, acid-catalyzed hydration, base-catalyzed hydration) 2. Which reagent is necessary for step 3? (Br2, HBr, H2/Pt, NaNH2, H20/H2SO4/HgSO4)
The answer choices for part b ["How would you convert the alkene to a epoxide?"] are: (a) Br2/NaNH2 in liq NH3; (b) mCPBA; (c) OsO4Thank you!
Alkynes generally undergo nucleophilic addition reactions. Ozonolysis of alkynes with O3, Zn and H3O+ yields either a carboxylic acid or carbon dioxide (or both). A. Both statements are true. B. Both statements are false. C. Only the first statement is true. D. Only the second statement is true.
Explain the following result. Although alkenes are generally more reactive than alkynes toward electrophiles, the reaction of Cl2 with but-2-yne can be stopped after one equivalent of Cl2 has been added.