What is the best way to prepare the following ethers using an alkyl halide and an alkoxide ion?a. CH3CH2CHOCH2CH2CH3CH3 c. OCH3 b. CH3CH2OCH2CHCH2CH2CH3CH3 d. CH2O

Q: What are the products of ozonolysis of 3,4-Dimethylhex-3-ene ? A 2 moles of Butan-2-one B…

A: Ozonolysis of 3,4-dimethylhex-3-ene gives 2 mole of butan-2-one

Q: 1. a. (E)-5-chloro-3-hexen-2-one Nomenclature b. 3-bromopentanal c. 4-bromoacetophenone d.…

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Q: Identify the best reagents to complete the following reaction. 1. NaOH А 2. CH3CH2CH2NH2 1. НСІ 2.…

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Q: Reaction of which compound with a Grignard reagent would yield a secondary alcohol following an acid…

A: Among these compounds that will react with grignard reagent to form secondary alcohol is given below

Q: Show how you might use the Williamson ether synthesis to prepare   ether

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Q: HO.

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Q: 20. (IR.2R)-Cyclopentane-1,2-diol 21. Ethyl 1-ethylpropyl ether 22. Di(p-chlorophenyl) ether 23.…

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Q: What are the products of ozonolysis of 3,4-Dimethylhex-3-ene ? A 2-Methylbutan-2-one and butanal B…

A: The given compound is 3,4-dimethylhex-3-ene.

Q: What are the hazards associated with: a) sodium methoxide and b) methanol? Draw the step by step…

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Q: What reagents are needed to convert each compound to benzaldehyde (CgHsCHO)? More than one step may…

A: a) C6H5CH2OH = The reagents needed to produce Benzaldehyde from the given reactant is,

Q: . Design a synthesis for cyclohexylmethylketone starting from 1,5-dibromopentane and using enol…

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Q: Why are epoxides more reactive than other ethers (open chain and larger cyclic ethers)? Select one:…

A: Please find your solution below : Epoxides are three-membered ring structure that have oxygen and…

Q: What reagent/s is needed for the given transformation? Br OH Br

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Q: 8. From the given starting material provide a reasonable synthetic route to the following molecule.…

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Q: how how you would use the Williamson ether synthesis to prepare the following ethers.You may use any…

A: The conversion of phenol to anisole is shown below.

Q: How would you prepare the following ethers? Use whichever method you think is more appropriate, the…

A: " Since you have posted a question with multiple sub-parts, we will solve first three sub-parts for…

Q: Explain the type of solvents favor SN2 & SN1 reactions & 3 examples      SN2      SN1

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Q: Which alkyl halide will react the fastest in an SN2 reaction (CH3)3CI CH3CH2Br CH3CH2I CH3I CH3Br

A: The SN2 reactions is used to denote bimolecular nucleophilic substitution. In this mechanism, a…

Q: What is the major product of a Friedel–Crafts alkylation using the following alkyl chlorides?a.…

A: Step 1) This is an aromatic electrophilic substitution which allows the synthesis of alkylated…

Q: What sets of reagents will result in an efficient Williamson ether synthesis (SN2)? ii Br ONa Br ONa…

A: The rate of SN2 reaction for alkyl halide is the highest for primary or 1° alkyl halide and lowest…

Q: I cyclohexanone II cyclohexanol III methylcyclohexanol. (b) Arrange the above compounds in the…

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Q: 14 Show the steps necessary to synthesize this compound by the Williamson ether synthesis. → phenyl…

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Q: Which of the following reactions describes why Acetic Anhyhdride needs to stay dry in order for it…

A: The acetic anhydride is need to stay dry because acetic anhydride in the presence of water gets…

Q: Unsymmetrical ethers can be made by the Williamson synthesis, in which an alkoxide ion reacts with…

A: We have to make the structures of alkoxide and alkyl bromide required to make this particular…

Q: 1- How would you prepare the following ethers? Use whichever method you think is more appropriate,…

A: Williamson synthesis is a method by which an alcohol is treated with an alkyl halide to yield an…

Q: 66. ALL of the following Ether can be prepared by Williamson's method, EXCEPT: A. Ditertbutyl ether…

A: Option (a)  In order to prepare di-tert- butyl ether, sodium tert-butoxide must be reacted with tert…

Q: What compounds will be a major product of the reaction sequence below (1) Br2, hv (2) Mg/ether он он…

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Q: Draw structural formulas for the alkoxide ion and the alkyl(aryl) bromide that may be used in a…

A: Here we are required to find the Starting material for the synthesis of ether.

Q: Which alkyl halide in each of the following pairs will react faster in an SN2 reaction with hydroxyl…

A: From the above diagram, it is clear that SN2 reaction with Hydroxyl ion is much more favourable to…

Q: Consider an E2 reaction between CH3CH2Br and KOC(CH3)3. What effect does each of the following…

A: (a)E2 elimination reaction: It is a second order elimination reaction and the rate of a reaction…

Q: Intramolecular reactions are also observed in Friedel–Crafts alkylation. Draw the intramolecular…

A: (a)

Q: Why is sodium hydroxide used in the smallest molar amount Explain the process of the "seeding"…

A: Since the NaOH is a strong base and it completely dissociates in an aqueous solution and produces a…

Q: fill in the product. which crown ether would be best to use in the following reaction to help the…

A: To dissolve the starting material, 18-Crown-6 with a molecular formula of C12H24O6 will be the best.

Q: 8. Provide the reagents necessary to prepare the following compound using a Williamson ether…

A: phenyl propylether is synthesised by the reaction of phenol and propyl iodide in the strong alkaline…

Q: When synthesizing acetals and ketals, what is the main driving force behind whether the reaction…

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Q: The SN2 reaction can be best carried out with   A. Primary alkyl halide B. Secondary alkyl halide…

A: The SN2 reaction can be best carried out with --

Q: A Grignard reagent can be produced by combining an alkyl bromide or alkyl chloride with.. A. LICI O…

A: General formula of Grignard reagent is RMgX where  R = alkyl group  Mg = magnesium  X = halogens

Q: Draw the major organic product for the reaction of this compound with PBr3.

A: A species with a larger size can easily accommodate negative charge. In other words, in a large size…

Q: Choose the best reagents to complete the reaction shown below. Br

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Q: Reagents 1. NaOH / H2O 2. H3O* SOCI2 i 1. NABH4 2. H3O* 1. ВНз / THF 2. H2O2 / NaOH f 1. LIAIH, 2.…

A: The organic reactions takes place by adding various reagents, to get the desired final product.

Q: A a. Draw the structure of both products B and C of these following transformations. ( 1) O3,…

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Q: Which statement is incorrect? Oa. A Grignard reagent is a strong lewis base O b. Water and alcohol…

A: When alkyl or aryl halides undergoe reaction with magnesium metal in ether medium, then there is a…

Q: Be sure to answer all parts. Draw a stepwise mechanism for the following reaction: HBr HO. Br Part…

A: Applying concept of SN1 reaction.

Q: Which ether cannot be prepared via a Williamson ether synthesis? OA di-1-naphthyl ether OR…

A: Williamson ether synthesis is an SN2 reaction between an organohalide and an alkoxide to form a…

Q: 1. “Alkyl" halides form Grignard reagents with elemental magnesium in ether solution. R-X + Mg(s)…

A: Synthesis of Grignard reagent.

Q: Which are the best reagents for the rxn ċ- CH3 First Step CH2 - N Second Step `CH2CH3 Third Step a.…

A: A question based on reduction reaction, which is to be accomplished.

Q: Which compound will react most rapidly with acetaldehyde? A.propylmagnesium chloride B.cyclopropyl…

A: Acetaldehyde show nucleophilic addition in which nucleophile attack on carbonyl carbon.

Q: Which would be the best reagent to make this anion? CH3C=CH CH3C=C" --> NAOH NaBr NaNH2 O Na/NH3

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Reactions of Ethers

Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.

Epoxides

Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.

Williamson Ether Synthesis

An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.