What is the chemoselectivity issue in the following reaction? You may wish to consult the datasheet NABH, Pd/C „CH, CH3 H,C H,C `N H In your answer you should cover the following points: • State whether the forwards reaction will be successful in producing the molecule shown or not • Explain why you think the forwards reaction would be successful or not • Describe other possible products of this reaction • Design an alternative way of making the product shown - stating all the reagents that you would use in each step of your reaction scheme
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
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