What is the effect of the absence of the leaving group (acetomethoxy) at the position 3 and substitution of a phenylglycyl (or ampicillin-like) substituent on the 7-aminoacyl portion of the molecule? 1. Increase oral activity and absorption 2. Greater resistance against B-lactamases 3. Enhance gram negative activity 4. Decreased antibacterial activity O 1 O 2 0 4

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter10: Reconstitution Of Powdered Drugs
Section: Chapter Questions
Problem 8.1P
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Please answer the question below:
What is the effect of the absence of the leaving group (acetomethoxy) at the position 3
and substitution of a phenylglycyl (or ampicillin-like) substituent on the 7-aminoacyl
portion of the molecule?
1. Increase oral activity and absorption
2. Greater resistance against B-lactamases
3. Enhance gram negative activity
4. Decreased antibacterial activity
O 1
O 2
O 4
Transcribed Image Text:What is the effect of the absence of the leaving group (acetomethoxy) at the position 3 and substitution of a phenylglycyl (or ampicillin-like) substituent on the 7-aminoacyl portion of the molecule? 1. Increase oral activity and absorption 2. Greater resistance against B-lactamases 3. Enhance gram negative activity 4. Decreased antibacterial activity O 1 O 2 O 4
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