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Small molecules binding to histone proteins also control gene expression by chromatin remodelling Group of answer choices No answer text provided. True No answer text provided. false

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter29: Transcription And The Regulation Of Gene Expression

Section: Chapter Questions

Problem 20P: Chromatin decompaction is a preliminary step in gene expression (Figure 29.48). How is chromatin...

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Epigenetic changes in chromatin remodelling which selectively PREVENTS transcription Acetylation and phosphorylation of certain histone proteins Methylation Group of answer choices NEITHER 1 NOR 2 2 ONLY 1 AND 2 1 ONLY
Hyperacetylation of histone tails is often associated with: Question 22 options: Tight conformation of chromatin Loose conformation of chromatin
Match the type of chromatin modification with the most likely effect on gene expression near the modified region. Each answer will be used once. -Increased expression -decreased expression -may increase or decrease expression a)Histone acetylation b)Histone methylation c)CpG methylation
Which region of chromatin is transcriptionally silent?a) Nucleoidb) Centromerec) Euchromatind) Heterochromatin
In eukaryotic chromatin, tightly coiled scaffolding proteins would indicate a region where genes are currently expressed at high levels. True or False
How does the CREB protein contribute to chromatin remodeling? Question 6 options: Inhibits HDAC via phosphorylation Activates HDAC via phosphorylation Inhibits HDAC via methylation Activates HDAC via acetylation
Chromatin decompaction is a preliminary step in gene expression (Figure 29.48). How is chromatin decompacted?
Match the terms with the most suitable description. ___ methylation a. makes a man out of you ___ SRY gene b. binding site for repressor ___ operator c. cells become specialized ___ Barr body d. can be epigenetic ___ differentiation e. inactivated X chromosome
Give typing answer with explanation and conclusion Which of the following regions of DNA would you expect to be transcribed. Select all the apply. Marks removed for incorrect selection(s) O a. Enhancer O b. 3' UTR O c. 5' UTR O d. Promoter
Changes in chromatin packing correlate with changes in gene expression in most cells. Why do you think this is the case?
Which is the expected outcome following the deacetylation of histones? a) Coiling of chromatin, preventing it from being accessed by transcriptional machinery b) Coiling of chromatin, allowing it to be accessed by transcriptional machinery c) Uncoiling of chromatin, preventing it from being accessed by transcriptional machinery d) Uncoiling of chromatin, allowing it to be accessed by transcriptional machinery
Possible genetic modifications that can cause epigenetic changes in gene expression include: A- all answers are correct B- histone acetylation C- chromatin remodeling D- histone variant localization e- DNA methylation