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What is the importance ofKRAS gene in the development of colorectal cancer. ?
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- What is the relationship between DM and development of Pancreatic Cancer? How can we prepare patients diagnosed with stage 4 Pancreatic CA for palliative care?Briefly outline some of the genetic changes commonly associated with the progression of colorectal cancer.Explain the importance of MSH2 and MSH6 in regards to adenocarcinoma colon cancer
- How the genes, when mutated, contribute to the development ofcancer ?explain and analyse each gene mutaition in the CIN, MSI, CIMP pathways and what are the causes of these mutations in regards to adenocarcinoma tumours colorectal cancer. Provide detailed analysis with examplesThe development of colon cancer is particularly well- studied, and often has a predictable order of mutations. Briefly describe the most common steps in the progression of colon cancer in the order of key genes mutated.
