mple. B-bromopyridine undergoes efficient exchange with n-bbasic tetrahydrofuran as solvent, and at this temperature, the alkly addition to the ring occurs, although the exchange can be cas typiperatures.9whatmecaniss mmBrn-BuliPHCNEt,0, -78 °C then aq HCIPh61%N.n also be prepared from bromo-pyridines at 0 °C via exchangTMSCH,Li) and lithium dimethylaminoethoxide (LIDMAE)react selectively a C-2) and from chlaMetal-halogen exchange with 2,5-dibromed 2,3-dibromopyridineuiuo metallation, 102Ilurtrates its trapping w

In the first step the 3-bromopyridine undergoes Li exchange with n-BuLi. In the next step the anion…

Answered: what ?s mecaniss Br n-Buli PHCN Ph.…

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what ?s mecaniss Br n-Buli PHCN Ph. Et20, -78 °C then aq. HCI 61%

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter20: Dienes, Conjugated Systems, And Pericyclic Reactions

Section: Chapter Questions

Problem 20.24P: Pyridine exhibits a UV transition of the type n at 270 nm. In this transition, one of the unshared...

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Bronsted Lowry Base In Inorganic Chemistry

Bronsted-Lowry base in inorganic chemistry is any chemical substance that can accept a proton from the other chemical substance it is reacting with.

Question

100%

mple. B-bromopyridine undergoes efficient exchange with n-b
basic tetrahydrofuran as solvent, and at this temperature, the alk
ly addition to the ring occurs, although the exchange can be c
as typi
peratures.9
what
mecaniss mm
Br
n-Buli
PHCN
Et,0, -78 °C then aq HCI
Ph
61%
N.
n also be prepared from bromo-pyridines at 0 °C via exchang
TMSCH,Li) and lithium dimethylaminoethoxide (LIDMAE)
react selectively a C-2) and from chla
Metal-halogen exchange with 2,5-dibrome
d 2,3-dibromopyridine
uiuo metallation, 102
Ilurtrates its trapping w

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