When a native protein in solution is heated to a high enough temperature, its polypeptide chain will unfold to become the denatured protein. The temperature at which a large portion of the protein unfolds is called the melting temperature. The melting temperature of a certain protein is found to be 47°C, and the enthalpy of denaturation is 3.80 × 102 kJ/mol. Assume that the denaturation is a two-state process; that is, native protein → denatured protein The single protein chain has 123 amino acids. Calculate the entropy of denaturation per amino acid.
When a native protein in solution is heated to a high enough temperature, its polypeptide chain will unfold to become the denatured protein. The temperature at which a large portion of the protein unfolds is called the melting temperature. The melting temperature of a certain protein is found to be 47°C, and the enthalpy of denaturation is 3.80 × 102 kJ/mol. Assume that the denaturation is a two-state process; that is, native protein → denatured protein The single protein chain has 123 amino acids. Calculate the entropy of denaturation per amino acid.
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter6: Thermochemistry
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Problem 68E: In a coffee-cup calorimeter, 1.60 g NH4NO3 is mixed with 75.0 g water at an initial temperature of...
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When a native protein in solution is heated to a high enough temperature, its polypeptide chain will unfold to become the denatured protein. The temperature at which a large portion of the protein unfolds is called the melting temperature. The melting temperature of a certain protein is found to be 47°C, and the enthalpy of denaturation is 3.80 × 102 kJ/mol. Assume that the denaturation is a two-state process; that is,
native protein → denatured protein
The single protein chain has 123 amino acids. Calculate the entropy of denaturation per amino acid.
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