When the drug theophylline is administered for asthma, a concentration below 5 mg/L has little effect and undesirable side-effects appear if the concentration exceeds 20 mg/L. For a body that weighs W kg, the concentration when M mg is present is 2M/W mg/L and the constant that measures the rapidity at which the concentration falls is T = 6 h. If a 500-mg tablet of the drug is taken by a person weighing 70 kg, after how many hours should the second dose be taken so as to prevent the drug from falling below the effective concentration? About 6 hours Once a day About 12 hours About 8 hours

Principles Of Pharmacology Med Assist
6th Edition
ISBN:9781337512442
Author:RICE
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Chapter5: Calculating Adult Dosages: Oral And Parenteral Forms
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When the drug theophylline is administered for asthma, a concentration below 5 mg/L has little effect and undesirable side-effects appear if
the concentration exceeds 20 mg/L. For a body that weighs W kg, the concentration when M mg is present is 2M/W mg/L and the constant
that measures the rapidity at which the concentration falls is T = 6 h.
If a 500-mg tablet of the drug is taken by a person weighing 70 kg, after how many hours should the second dose be taken so as to prevent
the drug from falling below the effective concentration?
About 6 hours
Once a day
About 12 hours
O About 8 hours
Transcribed Image Text:When the drug theophylline is administered for asthma, a concentration below 5 mg/L has little effect and undesirable side-effects appear if the concentration exceeds 20 mg/L. For a body that weighs W kg, the concentration when M mg is present is 2M/W mg/L and the constant that measures the rapidity at which the concentration falls is T = 6 h. If a 500-mg tablet of the drug is taken by a person weighing 70 kg, after how many hours should the second dose be taken so as to prevent the drug from falling below the effective concentration? About 6 hours Once a day About 12 hours O About 8 hours
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