Answered: Which of the following could be a…

Which of the following could be a reason(s) why a signalling cascade is interrupted, or turned 'off', once it has been turned 'on'?

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter4: Principles Of Neural And Hormonal Communication

Section: Chapter Questions

Problem 5RE: Second-messenger systems ultimately bring about the desired cell response by inducing a change in...

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Concept explainers

Cell Signaling

It allows cells to perform various cellular activities, coordinate, and interact with other cells. All cells of an organism receive signals from their environments and respond accordingly. Even the unicellular eukaryotes receive signals secreted by other cells and respond. In the case of yeast, mating takes place by signaling between the yeast cells. Communication by cell signaling in a multicellular organism has become a vast and important part of various fields of biology.

Question

Cellular signaling follows a cascade of events and has multiple points of regulation. Which of the following could be a reason(s) why a signalling cascade is interrupted, or turned 'off', once it has been turned 'on'?

A) a protein gets tagged with an ubiqutin group and gets degraded

B) a chemical modification occurred on serine, threonine, or tyrosine side chains to turn on/off proteins

C) allosteric regulation causes an active site to be hidden

D) All of the other answers are correct

E) The ligand is prevented from reaching the binding site

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