Which of the following is true about the sorting pathway for proteins destined for incorporation into lysosomes or the plasma membrane of eukaryotic cells? The SRP binds to the signal sequence soon after it appears outside the ribosome. O Binding of SRP to the signal peptide and the ribosome temporarily accelerates protein synthesis. The newly synthesized polypeptides include a signal sequence at their carboxyl termini. The signal peptide is cleaved off inside the mitochondria by signal peptidase. The signal sequence is added to the polypeptide in a post-translational modification reaction.

Which of the following is true about the sorting pathway for proteins destined for incorporation into lysosomes or the plasma membrane of eukaryotic cells? The SRP binds to the signal sequence soon after it appears outside the ribosome. O Binding of SRP to the signal peptide and the ribosome temporarily accelerates protein synthesis. The newly synthesized polypeptides include a signal sequence at their carboxyl termini. The signal peptide is cleaved off inside the mitochondria by signal peptidase. The signal sequence is added to the polypeptide in a post-translational modification reaction.

Name: 5 Which of the following is true about the sorting pathway for protein
Uploaded: 2024-03-20T06:42:55.000Z
Channel: Bartleby
Description: 5 Which of the following is true about the sorting pathway for proteins destined for incorporation intolysosomes or the plasma membrane of eukaryotic cells?The SRP binds to the signal sequence soon after it appears outside the ribosome.Binding of SRP

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter2: Cell Physiology

Section: Chapter Questions

Problem 11RE

See similar textbooks

Similar questions

The following are steps that occur when a protein is targeted for synthesis on the endoplasmic reticulum (ER). Which of the following indicates the correct sequence for the signal mechanism that targets proteins for the ER? The SRP leaves and polypeptide synthesis resumes, with simultaneous translocation across the membrane. Polypeptide synthesis begins on a free ribosome in the cytosol. An SRP binds to the signal peptide, halting synthesis momentarily. The rest of the completed polypeptide leaves the ribosome and folds into its final conformation. The SRP binds to a receptor protein in the ER membrane that is part of a protein complex that forms a pore. The signal peptide is cleaved by an enzyme in the receptor protein complex. A. 2, 3, 5, 1, 6, 4 B. 2 ,3, 5, 6, 1, 4 C. 3, 1, 6, 5, 2, 4 D. 3, 2, 1, 5, 6, 4
For each amino acid incorporated into a polypeptide the cell has to invest three high-energy phosphates (ATP or GTP). At which step of the overall process is energy investment NOT required? What is the correct answer from below? Ester bond formation between a tRNA and an amino acid Release of an aminoacyl-tRNA into the A-site of a ribosome Translocation of a ribosome along an mRNA molecule Peptide bond formation between amino acids none of the above
After pinocytic vesicles fuse with early endosomes, one possible fate of both cargo receptors and their cargo could be translocation to a new plasma membrane location, followed by exocytosis of the cargo molecule, which commonly occurs in human gut epithelial cells carrying which cargo? the human immunodeficiency virus (HIV) the glucose molecule the low density lipoprotein (LDL) the influenza virus the cholesterol molecule
Insulin is a protein that is produced by pancreatic cells and secreted into the bloodstream. Which of the following options correctly lists the order of the structures in the endomembrane system through which insulin passes from its production to its exit from the cell? rough ER, transport vesicles, Golgi apparatus, vacuole, cell membrane rough ER, Golgi apparatus, smooth ER, cell membrane rough ER, transport vesicles, cell membrane rough ER, lysosomes, transport vesicles, cell membrane
Which of the following statements best describes a signal peptide? A.A signal peptide is a short amino acid sequence present at the N-terminus of the majority of newly translated proteins destined for the endomembrane system. B.A signal peptide is a long amino acid sequence that is present at the C-terminus of a protein destined for the localization in lumen of the mitochondrial. C.A signal peptide is a glycan that is post-translational added to a protein to target that protein to the proteosome for degradation. D.A signal peptide is a postranslational modification that adds a lipid to a protein to help anchor the protein to a cellular membrane.
In eukaryotic cells, ribosomes are found both free in the cytosol and attached to the endoplasmic reticulum (ER). Proteins produced on the attached ribosomes are delivered to the ER, while proteins produced on free ribosomes are delivered to the cytosol. Briefly explain in one or two sentences the two processes in terms of the following: • ONE ultimate destination of a protein produced on an attached ribosome, and ONE general function of the protein (You do not need to identify the specific protein.) • ONE ultimate destination of a protein produced on a free ribosome, and ONE general function of the protein (You do not need to identify the specific protein.)
During the biosynthesis of ribosomes, rRNA synthesized in the (fill in) Nuclear membrane nucleolus Cytoplasm Nuclear pore complex And Ribosomal proteins are assembled together into the rirbosomal subunits which are then shipped to the cytoplasm where mature ribosomes are finally assembled. Free ribosomes are localized in the cytoplasm and synthesize cytoplasmic proteins such as [ans2]. While no protein synthesis takes place in the sER, it is an important site for the synthesis of (fill in) DNA tyrosine kinase receptors alcohol integrins tubulin proton pumps RNA phospholipids The sER plays also an important role in detoxification of different types of drugs, which is why ( fill in) Liver Bone Brain skin cells display a large sER. In addition, the sER functions as a reservoir for the storage of (fill in) Iron Iodine Calcium Sodium Ions in many type of cells
What is the pathway of a protein secreted from the cell. The protein is N-linked with glycosylation modifications.The starting point is when the mRNA attaches to the ribosome. What is the signal sequence for the protein? In the endomembrane.
For each of the following, identify the type of RNA involved (mRNA, rRNA, or tRNA). a. Transports the correct amino acid to the ribosome, using the information encoded in the mRNA. b. Is a major component of ribosomes. c. Speciﬁes the order of amino acids in a protein, using a series of three-base codons, where different amino acids are speciﬁed by particular codons. d. Contains a three-base anticodon that pairs with a complementary codon revealed in the mRNA. e. Assists in making the bonds that link amino acids together to make a protein.
Please draw or trace a pathway of any protein from translation to the plasma membrane. Name the protein (make sure it is a transemembrane protein). The protein in question must also have seceral protein modifications including, but not limited to, N-linked glycosylation, cysteine disulfide bonds, lipid modifications, and 3-D folding
In addition to vitamin A (retinoic acid), which other fat-soluble vitamin has been shown to make lysosomal membranes more unstable and vulnerable to rupture (when the cytosol is acidic)? vitamin E (in the form of a-tocopheryl succinate) vitamin B12 (in the form of cyanocobalamin) vitamin C (in the form of ascorbic acid) vitamin B2 (in the form of riboflavin) vitamin B1 (in the form of thiamine)
Occurring in the nucleus ribosome mitochondrion , translation transcription is the process of making an RNA copy from a DNA template. The molecule then enters the cytoplasm. The process in which the mRNA sequence is converted into a sequence of amino acids is called translation transcription . In the cytoplasm, the nucleus ribosome mitochondrion reads the amino acid sequence and assembles the protein.