The following are steps that occur when a protein is targeted for synthesis on the endoplasmic reticulum (ER). Which of the following indicates the correct sequence for the signal mechanism that targets proteins for the ER? The SRP leaves and polypeptide synthesis resumes, with simultaneous translocation across the membrane. Polypeptide synthesis begins on a free ribosome in the cytosol. An SRP binds to the signal peptide, halting synthesis momentarily. The rest of the completed polypeptide leaves the ribosome and folds into its final conformation. The SRP binds to a receptor protein in the ER membrane that is part of a protein complex that forms a pore. The signal peptide is cleaved by an enzyme in the receptor protein complex. A. 2, 3, 5, 1, 6, 4 B. 2 ,3, 5, 6, 1, 4 C. 3, 1, 6, 5, 2, 4 D. 3, 2, 1, 5, 6, 4
Proteins
We generally tend to think of proteins only from a dietary lens, as a component of what we eat. However, they are among the most important and abundant organic macromolecules in the human body, with diverse structures and functions. Every cell contains thousands and thousands of proteins, each with specific functions. Some help in the formation of cellular membrane or walls, some help the cell to move, others act as messages or signals and flow seamlessly from one cell to another, carrying information.
Protein Expression
The method by which living organisms synthesize proteins and further modify and regulate them is called protein expression. Protein expression plays a significant role in several types of research and is highly utilized in molecular biology, biochemistry, and protein research laboratories.
The following are steps that occur when a protein is targeted for synthesis on the endoplasmic reticulum (ER). Which of the following indicates the correct sequence for the signal mechanism that targets proteins for the ER?
- The SRP leaves and polypeptide synthesis resumes, with simultaneous translocation across the membrane.
- Polypeptide synthesis begins on a free ribosome in the cytosol.
- An SRP binds to the signal peptide, halting synthesis momentarily.
- The rest of the completed polypeptide leaves the ribosome and folds into its final conformation.
- The SRP binds to a receptor protein in the ER membrane that is part of a protein complex that forms a pore.
- The signal peptide is cleaved by an enzyme in the receptor protein complex.
A. 2, 3, 5, 1, 6, 4B. 2 ,3, 5, 6, 1, 4C. 3, 1, 6, 5, 2, 4D. 3, 2, 1, 5, 6, 4
Answer:
Introduction: Proteins are nourished into the ER at the time of translation if they consist of an amino sequence known as a signal peptide.
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