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Which of the following statements are TRUE? Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. A compound is an inhibitor of glyceraldehyde 3-phosphate dehydrogenase. If this compound were added to liver cells where D-glucose was the only substrate there would be an accumulation of those intermediates from glucose 6- phosphate to glyceraldehyde 3-phosphate and a depletion of those from 1-3 bisphosphoglycerate to pyruvate. a If in above case the substrate for the liver cells were L-lactate there would be no effect on the concentrations of glycolytic intermediates with the exception of the concentration of pyruvate increasing. The only constraint preventing glycolytic intermediates from leaving the cell is that they are all phosphorylated. When glucose is converted to lactate there is no overall change in the oxidation state because glyceraldehyde 3- phosphate dehydrogenase oxidizes glyceraldehyde 3-phosphate to 1-3 bisphosphoglycerate but lactate dehydrogenase reduces pyruvate to lactate. If all the glycolytic enzymes were incubated together under ideal conditions with ATP + ADP NAD+ and Pi the pyruvate produced would be only in an amount equivalent to that of the NAD+ present. The maximum yield of ATP derived by substrate phosphorylation starting with 2 molecules of Glucose and one molecule of Sucrose is twice that of Sucrose.

Which of the following statements are TRUE? Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. A compound is an inhibitor of glyceraldehyde 3-phosphate dehydrogenase. If this compound were added to liver cells where D-glucose was the only substrate there would be an accumulation of those intermediates from glucose 6- phosphate to glyceraldehyde 3-phosphate and a depletion of those from 1-3 bisphosphoglycerate to pyruvate. a If in above case the substrate for the liver cells were L-lactate there would be no effect on the concentrations of glycolytic intermediates with the exception of the concentration of pyruvate increasing. The only constraint preventing glycolytic intermediates from leaving the cell is that they are all phosphorylated. When glucose is converted to lactate there is no overall change in the oxidation state because glyceraldehyde 3- phosphate dehydrogenase oxidizes glyceraldehyde 3-phosphate to 1-3 bisphosphoglycerate but lactate dehydrogenase reduces pyruvate to lactate. If all the glycolytic enzymes were incubated together under ideal conditions with ATP + ADP NAD+ and Pi the pyruvate produced would be only in an amount equivalent to that of the NAD+ present. The maximum yield of ATP derived by substrate phosphorylation starting with 2 molecules of Glucose and one molecule of Sucrose is twice that of Sucrose.

Biochemistry
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter19: The Tricarboxylic Acid Cycle
Section: Chapter Questions
Problem 22P: Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is...
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Which of the following statements are TRUE? Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. A compound is an inhibitor of glyceraldehyde 3-phosphate dehydrogenase. If this compound were added to liver cells where D-glucose was the only substrate there would be an accumulation of those intermediates from glucose 6- phosphate to glyceraldehyde 3-phosphate and a depletion of those from 1-3 bisphosphoglycerate to pyruvate. a If in above case the substrate for the liver cells were L-lactate there would be no effect on the concentrations of glycolytic b. intermediates with the exception of the concentration of pyruvate increasing. The only constraint preventing glycolytic intermediates from leaving the cell is that they are all phosphorylated. no overall change in the oxidation state because glyceraldehyde 3- When glucose is converted to lactate there phosphate dehydrogenase oxidizes glyceraldehyde 3-phosphate to 1-3 bisphosphoglycerate but lactate dehydrogenase reduces pyruvate to lactate. If all the glycolytic enzymes were incubated together under ideal conditions with ATP + ADP+ NAD+ and Pi the pyruvate produced would be only in an amount equivalent to that of the NAD+ present. e The maximum yield of ATP derived by substrate phosphorylation starting with 2 molecules of Glucose and one molecule of Sucrose is twice that of Sucrose.
Transcribed Image Text:Which of the following statements are TRUE? Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. A compound is an inhibitor of glyceraldehyde 3-phosphate dehydrogenase. If this compound were added to liver cells where D-glucose was the only substrate there would be an accumulation of those intermediates from glucose 6- phosphate to glyceraldehyde 3-phosphate and a depletion of those from 1-3 bisphosphoglycerate to pyruvate. a If in above case the substrate for the liver cells were L-lactate there would be no effect on the concentrations of glycolytic b. intermediates with the exception of the concentration of pyruvate increasing. The only constraint preventing glycolytic intermediates from leaving the cell is that they are all phosphorylated. no overall change in the oxidation state because glyceraldehyde 3- When glucose is converted to lactate there phosphate dehydrogenase oxidizes glyceraldehyde 3-phosphate to 1-3 bisphosphoglycerate but lactate dehydrogenase reduces pyruvate to lactate. If all the glycolytic enzymes were incubated together under ideal conditions with ATP + ADP+ NAD+ and Pi the pyruvate produced would be only in an amount equivalent to that of the NAD+ present. e The maximum yield of ATP derived by substrate phosphorylation starting with 2 molecules of Glucose and one molecule of Sucrose is twice that of Sucrose.
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