Which of the following statements is correct regarding Dr Loewi's experiment? O a The results showed that electrical stimulation of the vagus nerve resulted in the release of a diffusible substance that could change the electrical activity of the heart Ob.The results showed that electrical stimulation of the vagus nerve resulted in the release of chloridh ions that hyperpolarized the heart O The results showed that electrical stimulation of the vagus nerve resulted in an increase in diffusion rate within the media by generating heat O d. The results showed that electrical stimulation of the vagus nerve resulted in the release of a diffusible substance that could enter the cells of the heart and reduce the membrane potential.

Human Physiology: From Cells to Systems (MindTap Course List)
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Chapter4: Principles Of Neural And Hormonal Communication
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Which of the following statements is correct regarding Dr Loewi's experiment?
O a. The results showed that electrical stimulation of the vagus nerve resulted in the release of a diffusible
substance that could change the electrical activity of the heart
O b. The results showed that electrical stimulation of the vagus nerve resulted in the release of chloridk ions that
hyperpolarized the heart
O. The results showed that electrical stimulation of the vagus nerve resulted in an increase in diffusion rate within
the media by generating heat
O d. The results showed that electrical stimulation of the vagus nerve resulted in the release of a diffusible
substance that could enter the cells of the heart and reduce the membrane potential.
Transcribed Image Text:Which of the following statements is correct regarding Dr Loewi's experiment? O a. The results showed that electrical stimulation of the vagus nerve resulted in the release of a diffusible substance that could change the electrical activity of the heart O b. The results showed that electrical stimulation of the vagus nerve resulted in the release of chloridk ions that hyperpolarized the heart O. The results showed that electrical stimulation of the vagus nerve resulted in an increase in diffusion rate within the media by generating heat O d. The results showed that electrical stimulation of the vagus nerve resulted in the release of a diffusible substance that could enter the cells of the heart and reduce the membrane potential.
Otto Loewi and the proof of electrochemical transmission.
In early physiology there was a lot of discussion as to whether nervous transmission was electrical or
chemical or both. Otto Loewi conducted the definitive experiment that showed electrochemical
transmission using frog hearts and the vagus nerve. Loewi knew that vagus nerve stimulation lowered
heart rate as shown below. So, he isolated a frog heart with its attached nerve, and measured the heart
rate before and after stimulating the vagus nerve with an electrical impulse.
Vagus
Stimulate
Stimulate vagus
nerve of heart 1
nerve
Heart 1
Frog
heart 1
Time (s)
If Dr Loewi had continued measuring for longer after stimulation, which of the following would have
occurred?
O The heart rate would remain low
O The heart rate would gradually return to the pre-stimulation level
O The heart rate would fluctuate between high and low
O The contraction force would remain low as the heart rate rose
O None of the above
Contraction force
Transcribed Image Text:Otto Loewi and the proof of electrochemical transmission. In early physiology there was a lot of discussion as to whether nervous transmission was electrical or chemical or both. Otto Loewi conducted the definitive experiment that showed electrochemical transmission using frog hearts and the vagus nerve. Loewi knew that vagus nerve stimulation lowered heart rate as shown below. So, he isolated a frog heart with its attached nerve, and measured the heart rate before and after stimulating the vagus nerve with an electrical impulse. Vagus Stimulate Stimulate vagus nerve of heart 1 nerve Heart 1 Frog heart 1 Time (s) If Dr Loewi had continued measuring for longer after stimulation, which of the following would have occurred? O The heart rate would remain low O The heart rate would gradually return to the pre-stimulation level O The heart rate would fluctuate between high and low O The contraction force would remain low as the heart rate rose O None of the above Contraction force
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