Which of the following statements is false? a mutation in a 5' or 3' splice site must alter the sequence of the protein encoded by a gene a mutation in a transcriptional terminator is unlikely to alter the sequence of a protein encoded by a gene. a mutation in a promoter is unlikely to alter the sequence of the polypeptide encoded by a gene a missense mutations replaces one amino acid with a different amino acid a frameshift mutation changes the sequence of a protein

Which of the following statements is false? a mutation in a 5' or 3' splice site must alter the sequence of the protein encoded by a gene a mutation in a transcriptional terminator is unlikely to alter the sequence of a protein encoded by a gene. a mutation in a promoter is unlikely to alter the sequence of the polypeptide encoded by a gene a missense mutations replaces one amino acid with a different amino acid a frameshift mutation changes the sequence of a protein

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter16: Gene Expression

Section: Chapter Questions

Problem 18RQ: IS. Alternative splicing has been estimated to occur in more than 95% of multi-exon genes. Which of...

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A bacterial species has a hypothetical sigma promoter that has the following sequence: TTGGCA - 18 bases - TATAAT What change in the level of transcription would there be if the sequence was mutated to: TTCGCA -18 bases -TATAAT 1.The mutation would move the promoter away from consensus and reduce the level of transcription 2.No change the consensus TATAAT sequence in the same. 3.The mutation would bind the promoter to the consensus and produce normal levels of transcription 4.The mutation would inhibit the promoter thereby inhibiting transcription
A bacterial species has a hypothetical sigma promoter that has the following sequence: TTGGCA - 18 bases - TATAAT What change in the level of transcription would there be if the sequence was mutated to: TTCGCA -18 bases -TATAAT Group of answer choices 1.The mutation would inhibit the promoter thereby inhibiting transcription 2.No change the consensus TATAAT sequence in the same. 3.The mutation would move the promoter away from consensus and reduce the level of transcription 4.The mutation would bind the promoter to the consensus and produce normal levels of transcription
The sigma factor protein's role in transcription in E. coli includes which of the following? None of the answer options are correct. plays a role in transcription termination forms part of the core enzyme required for transcription initiation helps the siRNA to bind to the promoter All of the answer options are correct. contributes to the proof-reading activity of RNA polymerase And The role of tRNA is to serve as an intermediate in the decoding of genes. serve as general translational components of the ribosome. facilitate protein trafficking in protein secretion. facilitate splicing of pre-messenger RNAs. act as vehicles bringing amino acids to the site of protein synthesis. None of the answer choices are correct.
You are investigating the impact of a gene mutation on the structure of the encoded protein and find that the encoded protein is substantially longer than normal, with the extra amino acids embedded within the normal amino acid sequence (not at either end). What type of mutation could cause this? Group of answer choices Mutation in a termination signal Mutation in the first AUG near the 5’ end Mutation at a splice site Mutation in the promotor Mutation in the poly-A signal
Mutation of which of these sequences would have an effect on translational initiation? A. 3’ UTR B. Polyadenylation signal C. 5’ UTR D. upstream enhancer E. TATA box
Gene X codes for a protein in eukaryotes. A mutated eukaryotic cell contains an altered base-pair in an intron of gene X. Which would be the most likely effect of this mutation on the biomolecules in the cell? The amount of pre-mRNA transcribed from gene X would be less than normal. The amount of functional protein corresponding to gene X would be less than normal. The ability of snRNAs to form a spliceosome would be diminished. The breakdown of mature mRNA corresponding to gene X would be faster
A particular mutation in the bacterial sigma factor allows this protein to bind RNA polymerase but prevents it from coming off (detaching) RNA polymerase once it binds. What specific effect will this mutation have on transcription? It will prevent the transcription termination exerted by the Rho protein. It will prevent the formation of closed complexes between RNA polymerase and the promoter. It will prevent the formation of open complexes between RNA polymerase and the promoter. It will prevent the transition from the transcription initiation to the transcription elongation stage. It will prevent the synthesis of abortive RNA transcripts while the RNA polymerase is bound at the promoter.
Regarding transcriptional promoter sites, which of the following statements are true? Select one or more than one: a)They are located in the gene (DNA) whose information will be transcribed b)They are found at the 3 'end of the gene that will be transcribed c)Some of them are called 'TATA box' d)They are found in the DNA, 'upstream' of the gene to be transcribed. e)They are proteins of the cytoplasm
The asterisk (*) in the diagram below indicates a single base mutation in the 5' splice site of the second intron of a eukaryotic gene. Due to this mutation, the second intron is now not ‘spliced out’ during the splicing process. What are the most likely consequences of this mutation with respect to the size of the pre-mRNA and the size of the mature mRNA? a. The pre-mRNA will be longer and the mature mRNA will be longer. b. The pre-mRNA will be longer and the size of the mature mRNA will not be affected c. The size of the pre-mRNA will not be affected and the mature mRNA will be longer d. The size of the pre-mRNA will not be affected and the size of the mature mRNA will not be affected
A mutation in the trp repressor gene that prevents the apo-repressor from binding the co-repressor What is the correct option from the choices below? causes the Trp repressor to permanently bind the trp operator. leads to a high level of transcription initiation from the trp promoter, even when tryptophan is present in the medium. does not lead to a high concentration of mRNA molecules that code for the structural genes trp E, D, C, B, A, when tryptophan is present in the medium, because attenuation of the operon will still work. a and b, but not c b and c, but not a
Which of the following statements about gene expression is false?a) More than one RNA polymerase can be transcribing a specific gene at a given time.b) More than one ribosome can be translating a specific transcript at a given time.c) Translation begins at a site called a promoter.d) Transcription stops at a site called a terminator.e) Some amino acids are coded for by more than one codon.
What are two reasons that a eukaryotic gene (e.g. Green Fluorescent Protein in jellyfish) will not be expressed if it is inserted into a bacterial genome with no alterations? a. Bacterial genes do not contain introns b. Bacterial promoters have different consensus sequences than eukaryotic ones c. Transcription of this gene is affected by the simultaneous processes of transcription and translation d.