Which statements are true? Explain why or why not.1 In terms of the way it interacts with DNA, thehelix–loop–helix motif is more closely related to the leu-cine zipper motif than it is to the helix–turn–helix motif.2 Once cells have differentiated to their final spe-cialized forms, they never again alter expression of theirgenes.3 CG islands are thought to have arisen during evo-lution because they were associated with portions of thegenome that remained unmethylated in the germ line.4 In most differentiated tissues, daughter cells retaina memory of gene expression patterns that were presentin the parent cell through mechanisms that do not involvechanges in the sequence of their genomic DNA.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter29: Transcription And The Regulation Of Gene Expression
Section: Chapter Questions
Problem 6P
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Which statements are true? Explain why or why not.
1 In terms of the way it interacts with DNA, the
helix–loop–helix motif is more closely related to the leu-
cine zipper motif than it is to the helix–turn–helix motif.
2 Once cells have differentiated to their final spe-
cialized forms, they never again alter expression of their
genes.
3 CG islands are thought to have arisen during evo-
lution because they were associated with portions of the
genome that remained unmethylated in the germ line.
4 In most differentiated tissues, daughter cells retain
a memory of gene expression patterns that were present
in the parent cell through mechanisms that do not involve
changes in the sequence of their genomic DNA.

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