Which two of the following materials combinations are most likely to cause osteolysis (loss of bone due to over activation of giant cells) in the medium-long term, when used as a bearing couple in the femoral head and acetabular liner in a total hip replacement? Select one or more: ✔a. Ultra-high molecular weight polyethylene + Yttria stabilized zirconia b. Ultra-high molecular weight polyethylene + Alumina (Aluminium oxide) c. Ultrahigh molecular weight polyethylene +316L Stainless steel Od. Alumina (Aluminium oxide) + Alumina O e. Cobalt Chrome + Cobalt Chrome

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