why are these sterically hindered what does it even mean to be stericaly hindered

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter9: Addition Via Cyclic Intermediate
Section: Chapter Questions
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why are these sterically hindered what does it even mean to be stericaly hindered
Steric Hindrance Favors the Elimination Product
However, if either the primary alkyl halide or the nucleophile/base is sterically hindered, then the
nucleophile will have difficulty getting to the back side of the a-carbon but will be able to remove
the more accessible proton. As a result, elimination will win the competition.
the primary alkyl halide is sterically hindered
Br + CH3O
the nucleophile is sterically hindered
Br +
Xó
40%
15%
+
60%
85%
CH3OH + Br
Хон
€
Transcribed Image Text:Steric Hindrance Favors the Elimination Product However, if either the primary alkyl halide or the nucleophile/base is sterically hindered, then the nucleophile will have difficulty getting to the back side of the a-carbon but will be able to remove the more accessible proton. As a result, elimination will win the competition. the primary alkyl halide is sterically hindered Br + CH3O the nucleophile is sterically hindered Br + Xó 40% 15% + 60% 85% CH3OH + Br Хон €
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