Why must the carrier of a genetic disease be heterozygous?

Q: A young lady requested pre-marital genetic counselling because her sister had died in infancy of…

A: Gangliosidosis refers to a group of lipid storage illnesses caused by the buildup of lipids called…

Q: What are the inheritance patterns and general clinical features of some common genetic disorders?

A: Genetic disorder  can be defined as the health problem  which caused by one or more abnormalities in…

Q: Do we know what genes cause Down syndrome?

A: In simple words, Gene can be defined as the basic physical and functional unit of heredity. Genes…

Q: Explain how it is possible for a person with a translocationor an inversion to be phenotypically…

A: Chromosomes are the condensed packaged structure of the genetic material of an organism. The…

Q: What is the difference between an autosomal dominant andautosomal recessive pattern of inheritance?

A: In autosomal dominant a character must express itself in each generation. It can not skip any…

Q: What are polytypic genes?

A: Genes are defined as the building blocks and the coded information that defines the complete physico…

Q: What is the karyotypefound in Down syndrome?

A: During the most recent years, Down disorder has been the focal point of uncommon consideration. Down…

Q: describe some of the human genetic disorders that are caused by nondisjunction?

A: Step 1 Nondisjunction is the non separation of homologous chromosomes during anaphase I that brings…

Q: What effects of heterozygosity for a deletion?

A: In a spontaneous deletion, 2 chromosomes break to remove the intervening segments. By deletion 1 or…

Q: What are the rarest genetic disorders?

A: The genetic disease refers to the type of disease that is caused by abnormalities in the genome.

Q: Why Many Inherited Diseases Result from Multiple Genetic Defects?

A: Genetic disorders : When health problems caused by abnormalities in genome. Abnormalities occur due…

Q: why why heterozygosity for a deletion can be harmful?

A: Deletion refers to a type of mutation in which the genetic material in a chromosome is deleted or…

Q: Which are the two kinds of biological abnormalities that could conceivably be inherited ?

A: Biological abnormalities refer to any condition of the body that alters from the normal parameter;…

Q: What is a gene with only one common, wild-type allele?

A: The coding region of the gene is known as allele. Wild-type alleles are the original form of the…

Q: What genetic criteria distinguish a case of extranuclear inheritance from (a) a case of Mendelian…

A: Extra nuclear inheritance is the type of inheritance pattern in which genetic information which is…

Q: What are Categories of Genetic Variants?

A: The difference in DNA sequence between organisms of a population is called genetic variation. These…

Q: What is an example of heterozygous genotype?

A: Genotype, the genetic makeup of an individual determines their physical characteristics and their…

Q: Why is the incidence of survivable genetic disorders involving deletions of parts of chromosomes so…

A: Deletions are the genetic aberrations or mutations in which a sequence of DNA or a segment of a…

Q: Which gene  is inherited from the father only?

A: A gene is a stretch of nucleotides present in the DNA molecule. It encodes information for the…

Q: How do we obtain two copies of each gene?

A: The fundamental unit of heredity is known to be as a gene. They are made of DNA and are found on…

Q: What is the genetic basis of the symptoms of Down syndrome?

A: Ans: In humans various diseases or disorders are caused by chromosomal aberrations or mutation in…

Q: Which one cannot be a reason for chromosome disjunction anomaly?

A: Disjunction anomaly  When the chromosomes of a cell unable to separate and each daughter cells got…

Q: What are genes located on the same chromosome?

A: Genetic recombination refers to the rearrangement of DNA sequences by the breakage and rejoining of…

Q: Why is autosomal Monosomy lethal?

A: Most living species have DNA as their genetic material. It is the cell's information centre,…

Q: What is the most common symptom in a genetic disorder and why? Do all people exhibit this symptom of…

A: Genetic disorder is a health problem that had resulted due to one or more abnormalities of a person'…

Q: What is Locus heterogeneity?

A: Inheritance of genetic diseases follows a simple Mendelian pattern of inheritance. Its study is…

Q: What occurs if the same genes are linked on the same chromosome ?

A: DNA, or deoxyribonucleic acid, is a form of nucleic acid found in the cell's nucleus. It is a…

Q: What is a recessive epistatic gene?

A: Epistasis Epistasis can be defined as the condition where phenotypic expression of one gene is…

Q: What is pleiotropy?

A: Pleiotropy refers to the expression of multiple traits by a single gene. These expressed traits may…

Q: What is the chromosome abnormality in cri du chat syndrome?

A: Cri-du-chat syndrome, commonly known as 5p- (5p minus) syndrome. Infants with this syndrome…

Q: What is the purpose of a pedigree?

A: Genetics is a branch of biology that is concerned with the study of Nucleic acids ( Ribonucleic…

Q: What does compound heterozygous mean and explain What causes heterozygous?

A:

Q: What kind of chromosomal mutations is/are produced by unequal crossing over?

A: Mutation refers to both the process of altering a gene or chromosome and the outcome of that…

Q: What does genetic heterogeneity mean?

A: The genetics is the branch of biology that deals with the study of genes, genetic variation and…

Q: What are mendelian disorders?

A: A Mendelian trait is one that is controlled by a single locus in an inheritance pattern. In such…

Q: How translocation Down syndrome arises?

A: Down’s syndrome is a genetic disorder that occurs mostly in children. It leads to intellectual…

Q: In the classic "X" figure of the chromosome, is the whole X from one parent, or is one side of the X…

A: Need to find whether the X of the chromosome is from whole chromosome or both from mother and…

Q: What chromosome is associated with autism?

A: Autism is a condition that appears at an early age of childhood. The person who suffers from autism…

Q: What are the possible effects of chromosomal rearrangements?

A: In genetics, a chromosomal rearrangement or Any alternation in the sequence of nucleotide in the…

Q: What is polygenic inheritance?

A: Sometimes a single phenotypic trait is the controlled by many genes together. Each gene can…

Q: Why is the incidence of survivable genetic disorders involving deletions of parts of chromosomes so…

A: Deletion is a type of mutation in which a part of DNA molecule is not copied during DNA replication.…

Q: What is a phenotype?

A: Phenotype is derived from two Greek words: phainein, which means “to show,” and typos, which mean…

Q: What types of chromosomal disorders are easily seen with a karyotype?

A: KARYOTYPE:- It is the complete set of chromosomes of an individual used to check for any…

Q: How do orthologous genes arise?

A:

Q: What is chromosome theory of inheritence?

A: Chromosomes are thread-like structures made up of chromatin.

Q: How does nondisjunction lead to abnormalities in chromosome number? Describe two types of genetic…

A: The failure of chromosome to seperate properly  during mitosis or meiosis is called nondisjunction…

Q: What are the possible effects of chromosomal mutations?

A: Malfunctioning of the kinetochore can lead to a chromosomal abnormality that is known as…

Q: What is the difference between polygeny and pleiotropy?

A: Biological inheritance, also called heredity, is the process by which different traits are passed on…

Q: What are some examples of Nondisjunction?

A: Non-disjunction refers to failure of the two members of a chromosome pair to segregate from one…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.