X-linked lissencephaly is an X-link dominant trait pertaining to a brain disorder. It superficially resembles an autosomal dominant trait because both the daughters and sons of an affected female parent can be affected. Mr. Panganiban is affected by the said disorder while his wife is not. Using your knowledge in predicting the genetic possibilities of the offspring, what do you think would happen to their sons and daughters in the first filial generation? Females affected by an X-link dominant have 50% for their sons and daughters to be affected. Father affected by the X-linked dominant trait can transmit the trait to all his daughters. Males with lissencephaly could transmit the genetic disorder for both sons and daughters. Lissencephaly is an X-link limited dominant trait. It usually affects males because they have only a single chromosome.

Biology Today and Tomorrow without Physiology (MindTap Course List)
5th Edition
ISBN:9781305117396
Author:Cecie Starr, Christine Evers, Lisa Starr
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Chapter9: Patterns Of Inheritance
Section: Chapter Questions
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X-linked lissencephaly is an X-link dominant trait pertaining to a brain disorder. It superficially resembles an autosomal dominant trait because both the daughters and sons of an affected female parent can be affected. Mr. Panganiban is affected by the said disorder while his wife is not. Using your knowledge in predicting the genetic possibilities of the offspring, what do you think would happen to their sons and daughters in the first filial generation?

  • Females affected by an X-link dominant have 50% for their sons and daughters to be affected.
  • Father affected by the X-linked dominant trait can transmit the trait to all his daughters.
  • Males with lissencephaly could transmit the genetic disorder for both sons and daughters.
  • Lissencephaly is an X-link limited dominant trait. It usually affects males because they have only a single chromosome.
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