You are a genetic councilor and your first patients of the day have arrived. They have both tested positive as "carriers" of the rare cystic fibrosis allele f. Therefore each of them have the genotype Ff. They want to have a family but are worried that they might have a child who is affected with this disorder (ff).   What is the probability that if they have a family of three children, two will be affected with cystic fibrosis, but exactly one of them will be unaffected.

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter16: Reproductive Technology, Genetic Testing, And Gene Therapy
Section: Chapter Questions
Problem 9QP: Cystic fibrosis is an autosomal disease that mainly affects the white population, and 1 in 20 whites...
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You are a genetic councilor and your first patients of the day have arrived. They have both tested positive as "carriers" of the rare cystic fibrosis allele f. Therefore each of them have the genotype Ff. They want to have a family but are worried that they might have a child who is affected with this disorder (ff).

 

What is the probability that if they have a family of three children, two will be affected with cystic fibrosis, but exactly one of them will be unaffected. You must show your work to receive full credit.

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