The pedigree shows inheritance of an autosomal recessive disease in an extended family. Assume unrelated individuals marrying into the family do not carry the disease, unless there is reason to believe otherwise. What is the chance that IV-2 and IV-4 will have a child with the disease? Individuals I-1, Il-5, III-5 and Ill-16 have the disease. III-18 6 7 89 10 11 12 13 14 15 16 4 III-19 IV IV-3 IV-4 IV-5 IV-6 V-1 IV-2 a. 1/8 O b. 1/12 O c. 1/16 O d. 3/16 C e. 1/24 f. 1/32 g. 3/32 h. 1/64
Q: The following pedigree represents the inheritance of an autosomal recessive disease in a certain…
A: Introduction Pedigree Analysis: this is the new approach to study the inheritance pattern in the…
Q: a. What type of inheritance is shown in the pedigree? 1 II 1 2 4 II 1 2 3 4 5 IV 1 Identify the…
A: Pedigree is a chart that represents members of a family affected by a genetic trait. Here, squares…
Q: Please consider the following pedigree. Assume that people who marry in to the family do not carry…
A: Pedigrees are interconnected diagrams to study and trace the particular trait over a few generations…
Q: The pedigree below shows a family tree for hemophilia, which is a sex-linked recessive disorder. 2.…
A: given: Hemophilia - sex-linked recessive disorder. Hemophilic male - XhY Hemophilic female - XhXh…
Q: Polydactly is an autosomal dominant phenotype. In this pedigree, I-2 has one copy of the dominant…
A: A condition in which a baby is born with one or more extra fingers is known as polydactyly. It's a…
Q: I. 1 2 4 II. 1 3 III. In the pedigree above, there could be carriers that are not marked. For each…
A: The pedigree analysis helps in identifying the mode of inheritance of a particular disease in a…
Q: The following pedigree shows a pattern of inheritance that is found in which of the following…
A:
Q: The pedigree below shows the inheritance of an autosomal recessive disorder in humans. Which of the…
A: Pedigrees are used to analyze the pattern of inheritance of a particular trait throughout a family.…
Q: The pedigree below shows inheritance of Tay-Sachs disease, an autosomal recessive trait, in two…
A: Tay-Sachs disease is an uncommon autosomal recessive neurological condition. It happens when the…
Q: The pedigree below shows the inheritance of a certain disorder. Based on the pedigree chart, is the…
A: Pedigree of dominant or recessive traits --A pedigree , diagram of family history presented by the…
Q: Why is there no trait (letter) on the y chromosome for males in this pedigree? A. Because the trait…
A: The genetic inheritance pattern is one of these kinds viz. autosomal recessive, autosomal dominant,…
Q: Using the pedigree, assume th
A: The pedigree chart is a diagram, which displays the appearance of the phenotypes of a particular…
Q: X-linked recessive, Unaffected. father Carrier mother XY |Unaffected ] Affected ICarrier XY…
A: A gene is a sequence of nucleotides in genome that codes for a functioning molecule. There is…
Q: Based on the pedigree, drag a claim about the inheritance pattern of sickle cell anemia into the…
A: Sickle cell anemia : in this disease the RBCs become sickle shaped, due to which the WBCs attack on…
Q: Wilson's disease is an inherited disorder in which there is too much copper in the body's tissue. It…
A: Given Wilson's disease is a autosomal recessive disease. It will only occurs if gene are…
Q: The pedigree shows inheritance of an autosomal recessive disease in an extended family. Assume…
A: Although the trait is skipped in the pedigree, autosomal recessive inheritance is discovered. The…
Q: Is this pedigree dominant or recessive? Autosomal or sex-linked? What is also usual about this…
A: The pedigree is the genetical analysis that gives us idea about the inheritance pattern of a…
Q: From this pedigree is it dominant or recessive. Is ur autosomal or sex-linked?
A: Pedigree is define a diagrammatic representation of the individuals of a family for a particular…
Q: pedigree when creating this one. Ray and Elaine were married in 1970. They both had normal vision.…
A:
Q: Is the inheritance pattern indicated by the shaded symbols in this pedigree consistent with the…
A: Inheritance or heredity is passing on one trait from the parents to the progeny by either asexual or…
Q: The pedigree below tracks the presence of dimples through a family's generation. Having dimples is…
A: Sir Gregor Mendel was a priest and a teacher who did the famous hybridization experiment on garden…
Q: I II II A
A: The genes located on the nuclear chromosomes obey the Mendelian law of inheritance. In the human…
Q: In the human pedigree shown below, black filled symbols indicate individuals suffering from a rare…
A: A pedigree is a diagram that shows an organism's ancestry and all direct and common predecessors,…
Q: A couple wants to have a child, but the mother has a brother that is affected by cystic fibrosis.…
A: Introduction Cystic Fibrosis Is An Autosomal Recessive Hereditary Condition Marked By The…
Q: The pedigree shown here involves a trait determined by a singlegene (affected individuals are shown…
A: Introduction Pedigree Analysis: this is the new approach to study the inheritance pattern in the…
Q: Determine the most likely mode of inheritance for the following pedigree: Question 5 options:…
A: Every human is made up of millions of cells. Cells are the basic structural and functional units of…
Q: . The pedigree below was obtained for a rare kidney disease.a. Deduce the inheritance of this…
A: Diseases have been researched extensively in the recent times. It is observed that diseases are not…
Q: One of the people on the chart is labeled with the letter A. Which of the following statements…
A: The genes located on the nuclear chromosomes obey the Mendelian law of inheritance. In the human…
Q: I. 3 4 II. 1 2 3 4 III. In the pedigree above, there could be carriers that are not marked. For each…
A: Pedigree analysis is the diagrammatic representation of the genetic inheritance of a trait of a…
Q: Polydactyly is an autosomal dominant condition in which an individual is born with more than five…
A: Sir Gregor Mendel was a priest and a teacher who did the famous hybridization experiment on garden…
Q: a. On the basis of this pedigree, what do you think is the most likely mode of inheritance for…
A: Humans carry 23 pair of chromosome - 22 pairs of autosomes and a pair of sex chromosomes. Sex…
Q: A typical pedigree for a family that carries neurofibromatosis is shown below. Note that carriers…
A: Neurofibromatosis (NF) is an autosomal dominant disorder. In autosomal dominant disorder, even the…
Q: The attached image is a pedigree of a family with a history of sickle cell anemia (the individuals…
A: Sickle cell anemia is a genetic condition caused by a mutation in the gene that codes for…
Q: ® Huntington's Disease is a rare neurodegenerative disorder caused by a defective gene. A pedigree…
A:
Q: identify each pedigree a and b as autosomal recessive or autosomal dominant. Write all the genotypes…
A: A pedigree chart displays a family tree, and shows the members of the family who are affected by a…
Q: Below is a pedigree chart of a certain family with a genetic disorder. Shaded individuals show…
A: The pedigree analysis deals with the study of the inheritance of genetic disorders. Genetic…
Q: Complete Punnett square based upon a cross between AO and OO blood types. (Hint: O is recessive.)
A: The possible genotypes and phenotypes can be examined by constructing a Punnett Square where the…
Q: You are a genetic counselor and you meet with a couple who are planning to have a baby. Fill in the…
A: If both of their parents are healthy that means both of their fathers have normal genotype. But…
Q: Red-green color blindness is an X-linked recessive trait. Heterozygous females have normal color…
A: 1. As male-7 is color blind female -2 must be a carrier as male-1 is not color-blind. 2. As males…
Q: Construct pedigree charts using the inheritance of hemophilia in figure 92 (page 113). This is…
A: Pedigree chart is a family tree helps to understand the inheritance of a particular trait or disease…
Q: The pedigree below shows inheritance of a particular autosomal trait across three generations. Males…
A: Pedigree is a family tree that is made up of symbols and line. Pedigree represents person’s family…
Q: The following pedigree illustrates the inheritance of Tay-Sachs disease in four generations of a…
A: A pedigree is defined as the family's history chart considering a particular given genetic trait.…
Q: Leigh's disease is a mitochondrially inherited disease with symptoms that include seizures, fatigue,…
A: A pedigree is a representation of inheritance of a trait across generations in a family.
Q: The following pedigree shows inheritance of Huntington's disease, a fatal genetic disorder that…
A: Huntington disease is a progressive brain disorder that causes uncontrolled movements, emotional…
Q: The pedigree below shows inheritance of Tay-Sachs disease, an autosomal recessive trait, in two…
A: Hi, Thanks For Your Question. Answer : Tay Sachs disease is a recessive autosomal condition. Only…
Q: Make a pedigree for each of the following situations. For each individual, write the individual…
A: The cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation causes this hereditary…
Q: The following pedigree describes the inheritance of Lesch-Nyhan syndrome, an X-linked recessive…
A: Lesch-Nyhan syndrome is a disorder that affects virtually entirely men. It is distinguished by…
Q: Write the genotype of the following individuals below based on the pedigree above. Please use…
A:
Q: The pedigree below traces the inheritance of a recessive disorder through a family. Affected…
A: Pedigree analysis can be defined as the tool which is used to study the inheritance of the genes in…
Please help finding the chance. Correct answer is 1/32
Trending now
This is a popular solution!
Step by step
Solved in 2 steps with 1 images
- A pedigree analysis was performed on the family of a man with schizophrenia. Based on the known concordance statistics, would his MZ twin be at high risk for the disease? Would the twins risk decrease if he were raised in an environment different from that of his schizophrenic brother?A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. What if the couple wanted prenatal testing so that a normal fetus could be aborted?A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. What is the chance that this couple will have a child with two copies of the dominant mutant gene? What is the chance that the child will have normal height?
- A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. Should the parents be concerned about the heterozygous condition as well as the homozygous mutant condition?As it turned out, one of the tallest Potsdam Guards had an unquenchable attraction to short women. During his tenure as guard, he had numerous clandestine affairs. In each case, children resulted. Subsequently, some of the childrenwho had no way of knowing that they were relatedmarried and had children of their own. Assume that two pairs of genes determine height. The genotype of the 7-foot-tall Potsdam Guard was A9A9B9B9, and the genotype of all of his 5-foot clandestine lovers was AABB. An A9 or B9 allele in the offspring each adds 6 inches to the base height of 5 feet conferred by the AABB genotype. a. What were the genotypes and phenotypes of all the F1 children? b. Diagram the cross between the F1 offspring, and give all possible genotypes and phenotypes of the F2 progenyAchondroplasia is a rare dominant autosomal defect resulting in dwarfism. The unaffected brother of an individual with achondroplasia is seeking counsel on the likelihood of his being a carrier of the mutant allele. What is the probability that the unaffected client is carrying the achondroplasia allele?
- The following pedigree shows the pattern of inheritance of red-green color blindness in a family. Females are shown as circles and males as squares; the squares or circles of individuals affected by the trait are filled in black. What is the chance that a son of the third-generation female indicated by the arrow will be color blind if the father is not color blind? If he is color blind?In Section 12.3, ''Laws of Inheritance," an example of epistasis was given for the summer squash. Cross white WAvYy heterozygotes to prove the phenotypic ratio of 12 white:3 yellow:l green that was given in the text.Could an individual with blood type O (genotype ii) be a legitimate child of parents in which one parent had blood type A and the other parent had blood type B?
- An allele responsible for Marfan syndrome Section 13.4 is inherited in an autosomal dominant pattern. What is the chance that a child will inherit the allele if one parent does not carry it and the other is heterozygous?Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior history of the disease. Consider the following pedigree (the darkly colored symbols represent affected individuals): a. Circle the individual(s) in which the mutation most likely occurred. b. Is the person who is the source of the mutation affected by retinoblastoma? Justify your answer. c. Assuming that the mutant allele is fully penetrant, what is the chance that an affected individual will have an affected child?A couple who are about to get married learn from studying their family histories that, in both their families, theirunaffected grandparents had siblings with cystic fibrosis(a rare autosomal recessive disease).a. If the couple marries and has a child, what is theprobability that the child will have cystic fibrosis?b. If they have four children, what is the chance that thechildren will have the precise Mendelian ratio of 3:1 fornormal:cystic fibrosis?c. If their first child has cystic fibrosis, what is theprobability that their next three children will be normal?