You are called in as a consult for a patient who suffers from acidosis. Urine levels of both lactic acid and isocitric acid are elevated. Mitochondria isolated from the patient’s fibroblasts oxidize pyruvate very slowly whereas α-ketoglutarate and malate are oxidized normally. a. At what enzyme would you predict the patient has a defect? b. Why? What evidence do you have to choose that enzyme? c. How do you account for the increase in lactic acid?

Q: 3) The following initial reaction rates were observed for the oxidation of Fe2• by Ce++ [Ce*] 1.5 x ...

A: Given :-  [Ce4+] = 2.3×10-5(M)  [Fe2+] = 1.8×10-5(M)  Initial rate when [Ce4+] = 2.3×10-5(M) and [F...

Q: Question 16 of 24 Submit Predict the location where a new substituent will be added when this aromat...

A:

Q: Describe the relationship between each of the pairs of isomers shown by recording Constitutional, Co...

A: The enantiomers are non super imposable mirror images of each other.  The Diastereomers are not mirr...

Q: pH

A:

Q: 19. One reaction of iron with hydrochloric acid is represented by the following thermochemical equat...

A:

Q: than one step. 1. CH,CH3ČCH, CH3CH2C=CH b) 1. CH3CH2CH2CHO CH3CH2CH2C=CH C=CH c=c-CH (0

A:

Q: Vhich reagent(s) would serve as the basis for a simple chemical test that would distinguish etween e...

A: Vinyl cyclohexane and ethylbenzene 

Q: he rate law and

A:

Q: (V) Consider solid and liquid samples of equal mass and heat capacity. If microwaves are fired at bo...

A: Since you asked multiple questions so as per Q&A guidelines of portal I solved first question fo...

Q: When 1 mol of a nonvolatile nonelectrolyte is dissolved in 4 mol of a solvent, the vapor pressure of...

A:

Q: 10. Consider a buffer prepared from the weak acid HF and its conjugate base F (shown below). What ha...

A:

Q: [OH"]

A:

Q: concentration

A:

Q: A beaker with 195 mLmL of an acetic acid buffer with a pH of 5.000 is sitting on a benchtop. The tot...

A:

Q: Use your molecular modeling kit to determine the absolute configurations of the following compounds....

A: Given : structure of molecules

Q: Calculate the approximate length of a PVA strand in centimeters, assuming that each monomer unit con...

A: The O-C-C bond point in PVA chain is three-sided plannar, bringing about a bond point of 120°. Nonet...

Q: boiling point?

A:

Q: A solution is prepared by dissolving 5.00 g of NaPH in 750.0 mL of water.   Determine the molar ou...

A: Part a: Given that, 5.0 g of NaOH is added to 750.0 mL of water. The molar mass of NaOH is 40 g/mol....

Q: Consider 3-methylpent-2-ene, if it undergoes hydroboration, which of the following final product is ...

A: Given - compound 3-methylpent-2-ene

Q: 1. Does the diagram best describe a crystalline solid, a liquid, or a gas? Explain.  2. In terms of...

A: Both a conventional fluid and a nematic fluid precious stone stage are liquids, however just in a ne...

Q: Why does hydrogel needs to be stable in water?

A:

Q: For the reaction, 2s02(g) + O2(g) - 2S03(g) at 450.0 K the equilibrium constant, Ko, has a value of ...

A:

Q: Define each stereocenter as either (R) or (S). If the molecule does not have a stereocenter select "...

A: ->Each chiral center has specific configuration R or S.  

Q: Calculate the density of [110] of W

A: Given:- Calculate the density of [110] of W. W is tungsten which is arranged in BCC crystal lattice.

Q: Which of the following is not a factor that could increase the rate of chemical reaction? O Increase...

A: ->Arrhenius equation is applicable to determine effect of temperature on rate of reaction.  

Q: Given the following set of data for the determination of density of solid material:Mass of empty bea...

A:

Q: plz solve all parts within 30-40 mins I'll give you multiple upvote

A: Initial amount of sodium-24 = 12 mCi Half life of sodium-24 = 15 hours   use the simple formula: per...

Q: An analytical chemist is titrating 139.8 mL of a 0.1600M solution of aniline (C,H,NH,) with a 0.6500...

A: Given that, 139.8 mL of 0.1600 M of aniline was titrated with 0.6500 M solution of HNO3.  The pKb of...

Q: Titanium(IV) chloride decomposes to form titanium and chlorine, like this: TiCl,(1)→Ti(s)+2Cl,(9) At...

A: The equilibrium constant is the ratio of the concentration of the gaseous product to that of gaseous...

Q: What is the theoretical yield of CaO if 24.8 g of CaCO3 is heated? O 9.65 g Cao O 16.13 g CaO O 11.3...

A: Given data : Mass of CaCO3 = 24.8 g MMolar mass of CaCO3 = 100.08 g/mol Molar mass of CaO = 56.08 g/...

Q: Consider a mixture of N2 and Ar in which there are three times as many moles of N2 as there are mole...

A: Ideal gas equation is PV=nRT where P, V, n, R and T represent pressure, volume, number of moles of g...

Q: Draw a pentapeptide, peptide sequence: IENAPE Show the position of all 'heavy' atoms with the approp...

A:

Q: A beaker contains a total of 500ml of solution which is 0.00050 M Ag*, 0.00050M Co²+, and 0.00010 M ...

A: Solubility product or Ksp is the product of concentration of ions in a solution. Higher the Ksp high...

Q: Liquid hexane (CH,(CH,) CH, will react with gaseous oxygen (0,) to produce gaseous carbon dioxide (C...

A: The complete combustion reaction of hexane + O2 is 2C6H14 + 19O2 --------> 12CO2 + 14H2O  

Q: Give the product(s), including all stereoisomers, of the reactions below. Is the product mirture opt...

A:

Q: For the following balanced reaction: 2H2 + O2 = 2 H2O How many grams of H2O (Molar mass: 18g/mol) w...

A: For the following balanced reaction: 2H2 + O2 = 2 H2O  

Q: e enthalpy change (AH)

A:

Q: 10. Determine whether each of the following solutions is unsaturated, saturated, or supersat- urated...

A:

Q: Choose the best explanation of why the hydroxy group is an o,p-director in electrophilic aromatic su...

A: why the hydroxy group is an o,p-director in electrophilic aromatic substitution reactions is given b...

Q: Suppose 18.7 g of zinc chloride is dissolved in 250. mL of a 0.60 M aqueous solution of potassium ca...

A:

Q: 3/4 1/2 ty x+

A:

Q: i) Explain why polypropylene is mainly produced by the coordination polymerization, but not by the f...

A: The solution of the question is given below:  

Q: Question #1: 1. A 10.17-g sample of solid sodium bicarbonate (the active ingredient in baking soda) ...

A: As per bartleby guidelines I answered only first question so please don't mind.Thanks in advance. 

Q: Given the following experimental data regarding "determination of molar mass of volatile liquid": ma...

A: Given the following experimental data regarding "determination of molar mass of volatile liquid": ma...

Q: What is the molar mass of methanol:  CH3OH ?

A:

Q: The total number of atoms present in one formula unit of Co2(SO4)3 is

A: Calculate each element....

Q: 4 Al (s) + 3 O2 (g) → → 2 Al203 (s) How many liters of O2 gas at 40 °C and 0.70 atm are required to ...

A:

Q: what is the importance of studying matter and mixtures in chemistry? explain.

A: Matter can be defined as the substance that has mass and occupy space. There are three states of mat...

Q: In the titration of 10.00 mL sample of vinegar solution with 0.550 M NAOH as titrant, the initial bu...

A:

Q: Solid ammonium sulfide is slowly added to 125 ml of a 0.0626 M manganese(II) acetate solution. The c...

A: Given data: [Mn2+] = 0.0626 M

Vitamins and Coenzymes

A class of organic compounds needed in the human body for normal activities is known as vitamins. They are characterized into two parts depending upon their solubility in water. They can act as coenzymes, cofactors, or prosthetic groups for enzymes.