Question

you are trying to come up with a drug to inhibit the activity of an enzyme thuogth to have a role in a liver disease. in the lab the enzyme was shown to have a Km of 1x10-6 M and Vmax of 0.1 micromoles/min.mg measruing at room temperature. you developed a mixed non-competitve inhibitor with a ki=0.4x10-6M and a Ki` pf 0/2 x 10-5 What will be the apparent Km in the presence of 1.0x10-6 M?

Expert Answer

Want to see the step-by-step answer?

Check out a sample Q&A here.

Want to see this answer and more?

Experts are waiting 24/7 to provide step-by-step solutions in as fast as 30 minutes!*

*Response times vary by subject and question complexity. Median response time is 34 minutes and may be longer for new subjects.
Tagged in
ScienceBiology

Biochemistry

Related Biology Q&A

Find answers to questions asked by students like you.

Q: Menkes disease in humans is caused by a mutation in a copper-transport protein that is coded for by ...

A: Hello. Since your question has multiple sub-parts, we will solve first three sub-parts for you. If y...

Q: . We commonly fight bacterial infections by developing a fever. Our body temperature may rise from a...

A: When the temperature of the body rises due to an infection, it is known as fever. Fever is caused by...

Q: How might the optimal temperature be affected by the growing conditions of the potato?

A: Potato is a tuber that grows under the soil. The soil temperature influences the growth of potatoes....

Q: The plate with 45 colonies was inocculated with 100 µL Volume of a 10^-8 Dilution. Given the formula...

A: Original cell density (OCD) can be found using the number of colonies of colony-forming units, volum...

Q: What are representatives of Hepaticophyta, Bryophyta, Anthocerophyta?  What are representatives of P...

A: Bryophytes are the group consisting of three types of non-vascular plants.The representatives of thi...

Q: What is the difference between a Polar covalent bond and non polar covalent bond?

A: The nonpolar covalent bond is a type of bond which occurs between two atoms that share a pair of an ...

Q: What is the effect of DCMU and sodium azide on motility in Chlamydomonas when each metabolic poison ...

A: Chlamydomonas:It is a genus of Chlorophyta (unicellular green algae). These algae are present in fre...

Q: Explain the importance of the following features in conjugating donor bacteria:  a. the origin of tr...

A: Hi, since there are multiple questions posted we will provide you with answers for the first three q...

Q: During successufl purification of every enzyme, the following may be expected: 1. Solubility in NaCl...

A: The specificity increases during the purification of every enzyme.