You prepare a squid giant axon and inject it with a tiny volume of solution containing 0.1 M NaCl and 0.1 M KCl in which both the Na+ and K+ ions are radioactively labeled. The two labeled ions are now inside the axon. You place this axon in a beaker containing seawater medium. The voltage gated sodium and voltage gated potassium channels are completely blocked using specific inhibitors - so they are closed If you now remove the voltage gated potassium channel inhibitor and keep the voltage gated sodium channel blocked, which of the radioactively labeled ions would you expect to appear within the seawater medium, while the neuron remained at rest (no stimulation of axon). Please explain If you now remove both the sodium and potassium voltage gated channel inhibitors - which of the radioactively labeled ions would you expect to appear most rapidly within the seawater medium, after the neuron had been stimulated to conduct a number of action potentials? Please explain

Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter39: Information Flow And The Neuron
Section: Chapter Questions
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You prepare a squid giant axon and inject it with a tiny volume of solution containing 0.1 M NaCl and 0.1 M KCl in which both the Na+ and K+ ions are radioactively labeled. The two labeled ions are now inside the axon. You place this axon in a beaker containing seawater medium. The voltage gated sodium and voltage gated potassium channels are completely blocked using specific inhibitors - so they are closed

  • If you now remove the voltage gated potassium channel inhibitor and keep the voltage gated sodium channel blocked, which of the radioactively labeled ions would you expect to appear within the seawater medium, while the neuron remained at rest (no stimulation of axon). Please explain

  • If you now remove both the sodium and potassium voltage gated channel inhibitors - which of the radioactively labeled ions would you expect to appear most rapidly within the seawater medium, after the neuron had been stimulated to conduct a number of action potentials? Please explain

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