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BIOLOGY:CONCEPTS+APPL.(LOOSELEAF)

10th Edition
STARR
ISBN: 9781305967359

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BuyFindarrow_forward

BIOLOGY:CONCEPTS+APPL.(LOOSELEAF)

10th Edition
STARR
ISBN: 9781305967359
Textbook Problem

The protist that causes malaria evolved from a photosynthetic ancestor and has the remnant of a chloroplast. The organelle no longer functions in photosynthesis, it remains essential to the protist. Why might targeting this organelle yield an antimalarial drug that produces minimal side effects in humans?

Summary Introduction

To determine:

The reason for targeting chloroplasts of protists, which cause malaria, to yield an antimalarial drug that produces negligible side effects in humans.

Introduction:

Plasmodium is the protist of apicomplexan genus and causes malaria. Humans get infected when the mosquito carrying Plasmodium sporozoites bites an individual. Apicomplexans are single-celled eukaryotic organisms that evolved from photosynthetic algae.

Explanation

Apicomplexans are a group of pathogens that cause infections such as malaria. These organisms contain a remnant chloroplast known as apicoplast. Apicoplast plays an important role in the growth and development of parasites.

The apicoplast is a potential target for drug therapy because it may provide parasite specificity...

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